Protein Alignment alpha-Est7 and Ces2h

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 606
• Identity: 179/606 - (29%)
• Similarity: 270/606 - (44%)
• Gaps: 130/606 - (21%)

  Fly    24 QYRQSTNETVVADTEYGQVRG-IKRLSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRD 87
            |.:.||:.  :..|..||:.| :..:...||...||.|||:|:||||.|||..|:.|.||..|||
Mouse    24 QGQDSTSP--IRTTHTGQILGSLIHMKDLDVGVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRD 86

  Fly    88 CSQPKDKAVQ------------VQFVFDKVEGSEDCLYLNVYTNNVKPDKAR-----PVMVWIHG 135
            .:......:|            ::........||||||||:|.    ||.|.     ||||||||
Mouse    87 GTSHPAMCLQDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYA----PDHAHEGSNLPVMVWIHG 147

  Fly   136 GGFIIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKN 200
            |..:||.|:. :.|......|:||:||||||||.|||.|  :.:....||.|..|||.||:|::.
Mouse   148 GSLVIGMASM-YDGSMLAAMENVVVVTIQYRLGVLGFFS--TGDERARGNWGYLDQVAALRWLQQ 209

  Fly   201 NCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICP--WAYNGDITHNPYR 263
            |.|.|||:|:.:|:||.||||.|...::::..:||||...|::||.|:..  .:.:.|:.:.  .
Mouse   210 NIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALISSLISVSSDVVYQ--T 272

  Fly   264 IAKLVGYKGEDNDKDVLEFLQN-VKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVIS 327
            :|.|.|.:..|:     |.|.| ::.|.    ||.::.:    ||   ||  .:.|.......:.
Mouse   273 VANLSGCEQVDS-----EALVNCLRGKS----EEEIMAI----NK---AF--KIIPGIVDGIFLP 319

  Fly   328 KPPKEMMKTAWSNSIPMFIG--NTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLATEPSKEK 390
            :.|:|:|.:|..:.:|..||  |..|.   |:     :|..:..:|:......:.:.|....:..
Mouse   320 RHPQELMASADFHPVPSIIGVNNDEYG---WI-----IPSSMSMIDSKKGMDRQMVQAILQRRAT 376

  Fly   391 LDSWSAQIRDV---HRTGSESTPD----NYMDLCSIYYFVFPALRVVHSRHAYAAGAPVYFYRYD 448
            ...|..::.|:   ...|....|.    .:.::...:.||.|||:|...:.::   |||:||.:.
Mouse   377 QMMWPPEVSDLLMEEYMGDNEDPQFLQVQFKEMMKDFTFVIPALQVAQFQRSH---APVFFYEFQ 438

  Fly   449 F------DSEELIFPYRIMRLGRGVKGVSHADDLSYQFSS--------------LLARRLPKESR 493
            .      ||:    |..:.        ..|.|::.:.|.|              ||:||:.|
Mouse   439 HRPSFFKDSK----PSHVK--------ADHGDEILFIFRSFWGGTQVDFTEEEELLSRRMMK--- 488

  Fly   494 EYRNIERTVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLN----ISDDLKFIDLPEW 554
                      .|..||...||.||      .|...|:...||....|:    :...||...|..|
Mouse   489 ----------YWANFARQRNPNSE------GLPYWPMFDQDEQYLQLDTQPAVGRALKTRRLQFW 537

  Fly   555 PKL---KVWE--SLYDDNKDL 570
            .|.   |:.|  .:.|.:|:|
Mouse   538 TKTLPEKIQELKDIEDRHKEL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	159/536 (30%)
		Aes	<116..>221	CDD:223730	52/109 (48%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	169/577 (29%)
		Aes	<127..>230	CDD:223730	52/109 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832875
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640