Protein Alignment alpha-Est7 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 646
• Identity: 175/646 - (27%)
• Similarity: 266/646 - (41%)
• Gaps: 174/646 - (26%)

  Fly     5 LGFVERLRWRLKTIEHKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDV--PYFSFEGIPYAQPP 67
            |||:. |..|..|         |:...||  :|.:|::||.:.....::  |...:.|:|||.||
Mouse    23 LGFLS-LVLRAST---------QAPAPTV--NTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPP 75

  Fly    68 VGELRFKAPQRPIPWERVRD-------CSQPKDKAV-----QVQFV--FDKV-----EGSEDCLY 113
            :||.||..|:.|..|..:|:       |.|....||     .|.|.  .|.|     |.:|||||
Mouse    76 IGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLY 140

  Fly   114 LNVYT-----------------------NNVKPDKARPVMVWIHGGGFIIGEANR------EWYG 149
            ||||.                       .:::...|:||||:||||.::.|..|.      ..||
Mouse   141 LNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG 205

  Fly   150 PDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITV 214
                   :|:::|:.||:|.|||:|  :.:....||.||.||:.||:|:..|.|.|||||..|||
Mouse   206 -------NVIVITLNYRVGVLGFLS--TGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITV 261

  Fly   215 FGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGYKGEDN---D 276
            ||...|.:....:.|:..::|||.|.|:|||||:..||.|    :.|.:...|:..|...|   .
Mouse   262 FGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVN----YQPVKYTSLLADKVGCNVLDT 322

  Fly   277 KDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKEMMKTAWSNS 341
            .|:::.|:...||:|  ||:::     :..:...||||.::     ..||...|:.:|:.....:
Mouse   323 VDMVDCLRQKSAKEL--VEQDI-----QPARYHVAFGPVID-----GDVIPDDPEILMEQGEFLN 375

  Fly   342 IPMFIGNTSYEGLLWVPEVKLMPQVLQQLD--AGTPF-------------IP--KELLATEPSKE 389
            ..:.:|....|||      |.:..|:...|  :||.|             .|  |:.| .|..|.
Mouse   376 YDIMLGVNQGEGL------KFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTL-RETIKF 433

  Fly   390 KLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRV--VHSRHAYAAGAPVYFYRYDFDSE 452
            ....|:      .|...|:.....:.|.:.:.:|.|::..  :|:|:    |:|.|||.:....:
Mouse   434 MYTDWA------DRDNPETRRKTLVALFTDHQWVEPSVVTADLHARY----GSPTYFYAFYHHCQ 488

  Fly   453 ELIFPYRIMRLGRGVKGVSHADDLSYQF-------SSLLARRLPKESREYRNIERTVGIWTQFAA 510
            .|:.|        .....:|.|::.|.|       :.|......|.......:..|  .||.||.
Mouse   489 SLMKP--------AWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMT--YWTNFAK 543

  Fly   511 TGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFI-------DLPEWPKLKVWESLY 564
            ||:|...                        :..|.|||       :...|.|....:.||
Mouse   544 TGDPNKP------------------------VPQDTKFIHTKANRFEEVAWSKYNPRDQLY 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	160/565 (28%)
		Aes	<116..>221	CDD:223730	45/133 (34%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	168/620 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		0/20 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832443
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740