Protein Alignment alpha-Est7 and Ces2c

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_663578.1
• Gene: Ces2c / 234671
• MGIID: 2385905
• Length: 561
• Species: Mus musculus
• Alignment Length: 612
• Identity: 187/612 - (30%)
• Similarity: 279/612 - (45%)
• Gaps: 140/612 - (22%)

  Fly    24 QYRQSTNETVVADTEYGQVRGIKRLSLYDVP-----YFSFEGIPYAQPPVGELRFKAPQRPIPWE 83
            |.:.|.....:.:|..||::|    ||..|.     ..:|.|||:|:||||.|||..|:.|.||.
Mouse    25 QGQDSPEANPIRNTHTGQIQG----SLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWS 85

  Fly    84 RVRD-------CSQPKDKAVQ-----VQFVFDKVEGSEDCLYLNVYTNNVKPDKAR-----PVMV 131
            .|||       |.|..|...:     ::.:......||||||||:||    |..|.     ||||
Mouse    86 GVRDGTAHPAMCLQNLDMLNEAGLPDMKMMLSSFPMSEDCLYLNIYT----PAHAHEGSNLPVMV 146

  Fly   132 WIHGGGFIIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALK 196
            |||||..:||.|:. :.|....:.||:|:||||||||.|||.|  :.:.:..||.|..||..||:
Mouse   147 WIHGGALVIGMASM-FDGSLLTVNEDLVVVTIQYRLGVLGFFS--TGDQHARGNWGYLDQAAALR 208

  Fly   197 WIKNNCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNP 261
            |::.|.|.|||:|:.:|:|||||||.|....:::..:|||||..|::||.|:.|...:.......
Mouse   209 WVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVALLPDLISETSEMVS 273

  Fly   262 YRIAKLVGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSL---EPFSTPE 323
            ..:|||.|.:..|:.    ..::.::.|.    |..:|.:    ||: |...|::   |.|
Mouse   274 TTVAKLSGCEAMDSQ----ALVRCLRGKS----EAEILAI----NKV-FKMIPAVVDGEFF---- 321

  Fly   324 CVISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQL-----------DAGTPFI 377
               .:.|||::.:...:.:|..||..:.|....:|.|....|:::.:           .|....:
Mouse   322 ---PRHPKELLASEDFHPVPSIIGVNNDEFGWSIPVVMGSAQMIKGITRENLQAVLKDTAVQMML 383

  Fly   378 PKE---LLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAG 439
            |.|   ||..|...:..|:.:.||:             :.::...:.||.|||:|.|.:.::
Mouse   384 PPECSDLLMEEYMGDTEDAQTLQIQ-------------FTEMMGDFMFVIPALQVAHFQRSH--- 432

  Fly   440 APVYFYRYDFDS---EELIFPYRIMRLGRGVKGVSHADDLSYQFSS--------------LLARR 487
            ||||||.:....   :::..|:        || ..|||::.:.|:|              ||:||
Mouse   433 APVYFYEFQHPPSYFKDVRPPH--------VK-ADHADEIPFVFASFFWGMKLDFTEEEELLSRR 488

  Fly   488 LPKESREYRNIERTVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISD----DLKF 548
            :.|             .|..||..|||.||      .|...||...||....|:|..    .||.
Mouse   489 MMK-------------YWANFARHGNPNSE------GLPYWPVMDHDEQYLQLDIQPAVGRALKA 534

  Fly   549 IDLPEWPKL---KVWE--SLYDDNKDL 570
            ..|..|.|.   |:.|  :..|.:::|
Mouse   535 GRLQFWTKTLPQKIQELKASQDKHREL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	166/542 (31%)
		Aes	<116..>221	CDD:223730	52/109 (48%)
Ces2c	NP_663578.1	COesterase	31..540	CDD:278561	179/583 (31%)
		Aes	<130..>233	CDD:223730	52/109 (48%)
		Prevents secretion from ER. /evidence=ECO:0000255	558..561		0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832719
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.640