Protein Alignment alpha-Est7 and Tg

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_006520808.2
• Gene: Tg / 21819
• MGIID: 98733
• Length: 2767
• Species: Mus musculus
• Alignment Length: 581
• Identity: 138/581 - (23%)
• Similarity: 224/581 - (38%)
• Gaps: 152/581 - (26%)

  Fly    25 YRQSTNETVVADT---------EYGQVRGIKRLSLYDVPY---FSFEGIPYAQPPVGELRFKAPQ 77
            ||:|....|.:|.         .:||::|..::......:   :.|.|:|||.||:.:.||:||:
Mouse  2182 YRKSGIPLVQSDVTSTPSVRIDSFGQLQGGSQVIKVGTAWKQVYRFLGVPYAAPPLADNRFRAPE 2246

  Fly    78 RPIPWERVRDCSQPKDKAVQVQFVFDKVEG---------SEDCLYLNVYT-NNVKPDKARPVMVW 132
             .:.|....|.::|:....|        .|         :||||||||:. .|:..:.:  |:|:
Mouse  2247 -VLNWTGSWDATKPRASCWQ--------PGTRTPTPPQINEDCLYLNVFVPENLVSNAS--VLVF 2300

  Fly   133 IH--------GGGFIIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLK 189
            .|        ||...|..:.....|       :.::||..||||..||:|..|.|  |.||.||.
Mouse  2301 FHNTMEMEGSGGQLTIDGSILAAVG-------NFIVVTANYRLGVFGFLSSGSDE--VAGNWGLL 2356

  Fly   190 DQVLALKWIKNNCASFGGDPNCITVFGESAGG--ASTHYMMLTDQTQGLFHRGILQSGSAICPWA 252
            |||.||.|::::..:|||||..:|:..:.:|.  ||.|.::.......||.:.:|..|||:.|.|
Mouse  2357 DQVAALTWVQSHIGAFGGDPQRVTLAADRSGADVASIHLLISRPTRLQLFRKALLMGGSALSPAA 2421

  Fly   253 YNGDITHNPYR-------IAKLVGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMF 310
                 ..:|.|       :||.||.. ..:.::|:..|:...|        |:  |.:...|::.
Mouse  2422 -----IISPERAQQQAAALAKEVGCP-TSSIQEVVSCLRQKPA--------NI--LNDAQTKLLA 2470

  Fly   311 AFGPSLEPFSTPECVIS-----KPPKEMMKTAWSNSIPMFIGNTSYEGLL-WVPEVKLMPQVLQQ 369
            ..|    ||.....|:.     :.|...:|......:.:.||.:..:||: ....||...:...:
Mouse  2471 VSG----PFHYWGPVVDGQYLRELPSRRLKRPLPVKVDLLIGGSQDDGLINRAKAVKQFEESQGR 2531

  Fly   370 LDAGTPFIP--KELLATEPSKEKLDS---WSAQIRDVHRTGSESTPDNYMDLCSI-------YYF 422
            .::.|.|..  :..|..|.|..::.:   |...:        |.:.|:|......       |:.
Mouse  2532 TNSKTAFYQALQNSLGGEDSDARILAAAVWYYSL--------EHSTDDYASFSRALENATRDYFI 2588

  Fly   423 VFPALRV-----------VHSRHA----------------YAAGAPVY-FYRYDFDSEELIFPYR 459
            :.|.:.:           |...|.                ||.|.|.| .|:..|.:||.....:
Mouse  2589 ICPMVNMASLWARRTRGNVFMYHVPESYGHGSLELLADVQYAFGLPFYSAYQGQFSTEEQSLSLK 2653

  Fly   460 IMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREY-RNIERTVGIWTQF--AATGNPYSE 517
            :|:                .||:.:....|....|: |........|..|  .|.|..|.|
Mouse  2654 VMQ----------------YFSNFIRSGNPNYPHEFSRKAAEFATPWPDFIPGAGGESYKE 2698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	134/574 (23%)
		Aes	<116..>221	CDD:223730	37/113 (33%)
Tg	XP_006520808.2	TY	34..93	CDD:238114
		TY	96..161	CDD:238114
		TY	301..359	CDD:238114
		TY	<612..658	CDD:238114
		TY	661..726	CDD:238114
		TY	730..>776	CDD:381826
		TY	<893..922	CDD:381826
		TY	1005..1074	CDD:238114
		TY	1150..1211	CDD:238114
		Ephrin_rec_like	1464..1509	CDD:311571
		TY	1519..1566	CDD:214561
		COesterase	2198..2717	CDD:365897	133/565 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930