Protein Alignment alpha-Est7 and Nlgn1

DIOPT Version :10

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 599
• Identity: 163/599 - (27%)
• Similarity: 250/599 - (41%)
• Gaps: 152/599 - (25%)

  Fly    20 HKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDV--PYFSFEGIPYAQPPVGELRFKAPQRPIPW 82
            |.:.|.....:..|.  |.:|::||||:....::  |...|.|:|||.||.||.||:.|:.|.||
Mouse    42 HVLSQKLDDVDPLVT--TNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPW 104

  Fly    83 ERVRDCSQ-----PK--------DKAVQVQFV--FDKV-----EGSEDCLYLNVY--TNNV---- 121
            ..:|:.:|     |:        :..:.|.|.  .|.|     :.||||||||:|  |.:|
Mouse   105 SDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRIS 169

  Fly   122 -----KPDK---------------------------------ARPVMVWIHGGGFIIGEAN---- 144
                 ||.|                                 .:||||:||||.::.|..|
Mouse   170 KECARKPGKKICRKGGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDG 234

  Fly   145 --REWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGG 207
              ...||       :|:::|:.||||.|||:|  :.:....||.||.|.:.||:|...|...|||
Mouse   235 SVLASYG-------NVIVITVNYRLGVLGFLS--TGDQAAKGNYGLLDLIQALRWTSENIGFFGG 290

  Fly   208 DPNCITVFGESAGGASTHYMML---------TDQTQGLFHRGILQSGSAICPWAYNGDITHNPYR 263
            ||..|||||..|||:..:.:.|         ::.|:|||.|.|.|||:|:..||    ::..|.:
Mouse   291 DPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWA----VSFQPAK 351

  Fly   264 IAKLVGYKGEDNDKDVLEF---LQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECV 325
            .|:::..|...|..|.:|.   ||....|:|  |:::|     :..:...||||.::     ..|
Mouse   352 YARILATKVGCNVSDTVELVECLQKKPYKEL--VDQDV-----QPARYHIAFGPVID-----GDV 404

  Fly   326 ISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLD---AGTPFIP--------K 379
            |...|:.:|:.....:..:.:|....|||.:|..:......:...|   |.:.|:.        |
Mouse   405 IPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGK 469

  Fly   380 ELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRV--VHSRHAYAAGAPV 442
            ::| .|..|.....|:      .|...|:.....:.|.:.:.:|.||:..  :||..    |:|.
Mouse   470 DVL-RETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNF----GSPT 523

  Fly   443 YFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQF-------SSLLARRLPKESREYRNIER 500
            |||.:....:....|        .....:|.|::.|..       :.|......|.......:..
Mouse   524 YFYAFYHHCQTDQVP--------AWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 580

  Fly   501 TVGIWTQFAATGNP 514
            |  .||.||.||:|
Mouse   581 T--YWTNFAKTGDP 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	34..514	CDD:395084	159/583 (27%)
Nlgn1	XP_006535478.1	COesterase	52..646	CDD:395084	161/589 (27%)