Protein Alignment alpha-Est7 and cest-16

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 627
• Identity: 174/627 - (27%)
• Similarity: 268/627 - (42%)
• Gaps: 151/627 - (24%)

  Fly    38 EYGQVRGIKRLSLYDVP---YFSFEGIPYAQPPVGELRFKAPQRPIPW-------ERVRDCSQPK 92
            |.|.|||    ::|::.   ...|.|:|||:||:||||||.|.:...|       |....|.|..
 Worm    29 EQGLVRG----NIYNIDGKHIQIFRGVPYAEPPIGELRFKPPVKKTRWHQELPAVEYGPPCLQFM 89

  Fly    93 DKAVQVQFVFDKVE-GSEDCLYLNVYTNNVKPDKAR--PVMVWIHGGGFIIGEANREWYGPDY-- 152
            |.....:|....:: .|||||||||::.....|:::  |::||||||.|:.|.|:.   |.|.
 Worm    90 DFHKNDKFAKTNMDRQSEDCLYLNVFSPYDTDDESKTYPILVWIHGGSFLAGSADT---GIDMEV 151

  Fly   153 ----FMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCIT 213
                .:.:.:..|:|.||||.||||:.::.: .:.||.|:.|.|:||:||::|...|.|||..:|
 Worm   152 IAANIVSKGIAFVSINYRLGPLGFMNYQNGD-KLEGNFGIWDMVMALQWIQSNIKQFNGDPTKVT 215

  Fly   214 VFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHN--PYRIAKLVGY------ 270
            |.|||||||::..:.|:.:|.||.|:.|:.|||::..||.:   .|:  .|.:..||.|
 Worm   216 VMGESAGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIH---RHSQPAYSVDNLVAYFRCEKW 277

  Fly   271 KGEDNDKDVL--EF--------------LQNVK----AKDLIRVEE-NVLTLEERMNKIMF---- 310
            ..||:.|:|:  |:              .||||    ..|:.:::: |.|..|...:..:|
 Worm   278 INEDDTKEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDDMTQMDKMNCLRKELNFSSPLFRKAL 342

  Fly   311 --AFGPS-------LEPFSTPECVISKPPKEMM----KTAWSNSIPMFIGNTSYEGLLWVPEVKL 362
              ..|.|       |.|.|....|.:.....:|    :..|.:...||......:||   ....:
 Worm   343 AAELGVSKMVVDGDLVPSSGVSLVRNNARIPIMTGVARKEWGHKKAMFYNMHQRDGL---KRSDV 404

  Fly   363 MPQVLQQLDAGTPFIPKELLATEPSKEKLDSWSAQ-------IRDVHRTGSESTPDNYM----DL 416
            ..||.:.:|..         ..|.:.|||.:.:.|       :|.:....:|...|..:    .|
 Worm   405 EEQVYRIIDNS---------FHETASEKLANSTVQLIANATIVRYLETPNNEFIADQVVGALQKL 460

  Fly   417 CSIYYFVFPALRVVHSRHAYA-AGAPVYFYRYDF-------DSEELIF------PYRIMRLGR-- 465
            .|...||.|..|.|   .||. .|.|||.|.:|:       :||..|:      |..:.|..:
 Worm   461 ESDIEFVAPCEREV---AAYVDKGVPVYLYSFDYVPKSPILESERKIYSLFGTKPVEMKRTEKSE 522

  Fly   466 -----GVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVG-----IWTQFAATGNPYSEKI- 519
                 ...|:.||...|..:||..      |...|...|.|:.     :.|.|...|:|.:.:.
 Worm   523 ILEKAAFHGLDHAFIFSKGYSSNF------EISPYTKREETMSKILCTMLTNFVKNGDPSTTRFS 581

  Fly   520 ------NGMDTLTID-PVRKSDEVIKCLNISDDLKFIDLPEW 554
                  |....:::| |::.         :..::.|.|...|
 Worm   582 WPIFSGNSSQYVSLDVPLKL---------LEGEIHFPDAQFW 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	167/577 (29%)
		Aes	<116..>221	CDD:223730	44/112 (39%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	171/619 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810