Protein Alignment alpha-Est7 and glit-1

DIOPT Version :10

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 576
• Identity: 143/576 - (24%)
• Similarity: 236/576 - (40%)
• Gaps: 173/576 - (30%)

  Fly    31 ETVVADTEYGQVRGIKRLSLYDVPY------------------------------FSFEGIPYAQ 65
            :.||.....|.:.| |.:.|:::|:                              |:|.|:|||:
 Worm    53 DEVVVRLPLGDIVG-KEVHLHNLPWTIHKDPTEELPKDGTHFDPNPLKPKNNITVFTFLGVPYAE 116

  Fly    66 PPVGELRFKAPQ--------RP-IPWERVRDCSQPKDKAVQ------VQFVFDKVEGSEDCLYLN 115
            ||..:.|||.||        :| :.:.....|:|..:|:..      ..|:.|     |||||||
 Worm   117 PPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQDVEKSPSPFVDHPYPFMVD-----EDCLYLN 176

  Fly   116 VYTNNVKPDKAR------PVMVWIHGGGFIIGEANREW--YGPDYFMKEDVVLVTIQYRLGALGF 172
            :::    ||.::      ||:|:.|||.|..|.|| ||  :|   .....:|:||:.|||||.||
 Worm   177 IFS----PDISKNAQTTYPVIVFFHGGNFQTGSAN-EWPAHG---LASRGMVVVTVNYRLGAFGF 233

  Fly   173 MSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLF 237
            ||:...|   .||.||:||.|||:::|||..:|||||..:||.|..||.||..:.|.:..::.||
 Worm   234 MSMGDSE---TGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHLF 295

  Fly   238 HRGILQSGSAICPWAYNGDITHNPYRIAKLVGYKG--------------EDNDKDVLEFLQNVKA 288
            ......||:.:...:|.|..........||..|.|              ..:..|:::..:|
 Worm   296 RSAATMSGAEVSYHSYIGKTALAFNNTMKLGRYAGCTQAVAQHRWDCILTRSTGDIIDATRN--- 357

  Fly   289 KDLIRVEENVLTLEERMNKIMFAFGPSLE----PFSTPECVISKPPKEMMKTAWSNSIPMFIGNT 349
               |.:|.|           .:.|.|:::    |.:....:::.|..|   |:..:.:||.||..
 Worm   358 ---IPIEYN-----------RYLFMPTVDGKYLPGNPLWTLVNAPSGE---TSIMSPVPMLIGMN 405

  Fly   350 SYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLATEPSKEKLDSWSAQ--IRDVHRTGSESTPD- 411
            :.:|...|.|.:.:.:..|..|.              ..|.|.|:|.:  .|..:....|:|.|
 Worm   406 AQDGSEVVLEDRRLGEFSQFNDV--------------DHEYLKSYSLEYCYRHNYSMNREATADA 456

  Fly   412 -------------------NYMDLCSIYYFVFPALRVVHSRHAYAAGAPVYFY--RYDFDSEE-- 453
                               |::...:..|:..| :::....|: ::|:.|:.|  .|:|..:.
 Worm   457 ILSKYTFWPDRAAAWAIKENFIQFATDAYYTAP-MQLSSHLHS-SSGSRVFQYVNNYNFSRQHPN 519

  Fly   454 -----------------LIFPYRIM---RLGRGVKGVSHAD---DLSYQFSSLLAR 486
                             |:|.|..:   ....|::|::..|   :.|..||:::.|
 Worm   520 LLFIPDWMGVCRDCDLYLMFGYPFLPDELRPIGLRGINFTDTDRNASRTFSNIIRR 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	34..514	CDD:395084	142/573 (25%)
glit-1	NP_508807.1	alpha/beta hydrolases	98..629	CDD:473884	136/530 (26%)