Protein Alignment alpha-Est7 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 581
• Identity: 154/581 - (26%)
• Similarity: 248/581 - (42%)
• Gaps: 110/581 - (18%)

  Fly    32 TVVADTEYGQVRGIKRLSLY---DVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQ--- 90
            |.|.:...|.:||    ::|   |.....:.|||:|:.|:|:||||.......|.:..||.:
 Worm    14 TEVFNASCGPIRG----NVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGP 74

  Fly    91 --PKDKAVQVQFVFDKVE---GSEDCLYLNVYTNNVKP---DKARPVMVWIHGGGFIIGEANREW 147
              |:..|:....|.....   ..::||.|||:....|.   ....||||:.:||||.:|.::
 Worm    75 GCPQSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGFSS--- 136

  Fly   148 YGPDYFMK-----EDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGG 207
            ...||.:.     :||:|||..||:|.|||.:.......  ||.||.||.|||:|::.:..||||
 Worm   137 MFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVAR--GNWGLWDQALALQWVQKHIKSFGG 199

  Fly   208 DPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNG-DITHNPYR-IAKLVGY 270
            ||:.:|:.|.||||||..::.|:......|.:.|..||:|.||:.... |:....:| .|...||
 Worm   200 DPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFANHHGY 264

  Fly   271 KGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKEMMK 335
            .|.|: |.:|::.|:..::..::.|........     ||:|.|:.:....|     ||..|:.|
 Worm   265 TGNDS-KSLLQWYQSQDSEIFLKAEGYKCPASG-----MFSFVPNFDGDFFP-----KPFDELRK 318

  Fly   336 TAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLAT-----------EPSKE 389
            .|......:.||  .||||           ..:...||.. .|:::|:.           |..|.
 Worm   319 EAPKLGAIVSIG--EYEGL-----------GFEDFYAGQK-TPQQMLSAALGPEVVRNREEVVKR 369

  Fly   390 KLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAGAPVYFYRYDF--DSE 452
            ..:|:   :::......|:.....:::...|||...|...|.|...|  |..||.|.:::  .:.
 Worm   370 AAESY---LKNGGNENEENIAKTLVEIFGDYYFSVGAFDTVRSLVKY--GNTVYLYSFNYFNPNT 429

  Fly   453 ELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVGIW-TQFAATGNPYS 516
            .::|     ...|.....:|..||.|.|    .....:.|:|.|.:...:|.: |.||..|||
 Worm   430 PIVF-----GKNRPFNAANHGSDLRYIF----GEGTGEFSKEDRQVMDMMGTYHTNFAKYGNP-- 483

  Fly   517 EKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLP------EWPKLKVWESLYDDNKDLL 571
               ||                |.:::..:...:|.|      ::||.::.::..|....::
 Worm   484 ---NG----------------KGVSVPWEKYSLDNPGRYFKIDYPKCEMADNFLDGRHKII 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	144/516 (28%)
		Aes	<116..>221	CDD:223730	44/112 (39%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	153/569 (27%)
		Aes	<105..>239	CDD:223730	53/138 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157288
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650