Protein Alignment alpha-Est7 and cest-10

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 605
• Identity: 137/605 - (22%)
• Similarity: 232/605 - (38%)
• Gaps: 167/605 - (27%)

  Fly    31 ETVVADTEYGQVRG--IKRLSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRD------ 87
            ::|:.:|..|::.|  |....|       |:.||:|:||:|:|||:.||....|..||:
 Worm    20 DSVIVETSLGKLNGDQIGNFHL-------FKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKDYGP 77

  Fly    88 -CSQPKDKAVQVQFVFDKVEGSEDCLYLNVYTNNV-KPDKARPVMVWIHGGGFIIGEA---NREW 147
             |.........||...|     ||||:||::|:.. ...|...|::::|||......|   |
 Worm    78 ACMSNSSTTKTVQKWVD-----EDCLHLNIFTSETCLKSKNCAVVIYLHGGNLHYDSAVMFN--- 134

  Fly   148 YGPDYFM-----KEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGG 207
               |.|:     .:::|.|....|||......::...: .|.|..|.|.:.|:::.|::..:|||
 Worm   135 ---DTFLLHTYASQEIVFVIPAVRLGIFSHFVVEDQSI-APNNLALFDMLQAMEFAKSDIHNFGG 195

  Fly   208 DPNCITVFGESAGGASTHYMMLTDQTQ-----GLFHRGILQSGSAICPWAYNGDI----THNPYR 263
            :....|:.|.|.||  |...||:..|:     .||.:.|..|...      |.|.    ....||
 Worm   196 NNKRTTLLGHSYGG--TVASMLSFSTKVNTDLSLFQQYISMSSPT------NFDTLELQVERTYR 252

  Fly   264 IAKLVGYKGED------NDKDVL--EFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFS 320
            .|:......::      |.|:|.  :.|:...|.:|:|::.   :|||....:   :|.|
 Worm   253 FAEHANCLPKNSKFMRKNQKEVYMRDCLKKKSASELLRIQR---SLEEAGYPV---YGGS----- 306

  Fly   321 TPECVISKPP--KEMMKTAW---SNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKE 380
                 :.:.|  :|:::..:   .|:|....|.|.||.|:: ...:.|.:.|
 Worm   307 -----VMRGPIFQEVLERDFMDSPNNITSLTGCTKYESLVY-DHYRNMGKAL------------- 352

  Fly   381 LLATEPSKEKLDSWSAQIRDVHRTGSESTP---DNYMDLCSIYYFVFPALRVVHSR--HAYAAGA 440
                     ..:::. ::.:.:|:.|:...   ||..:...|      .|..:.:|  .......
 Worm   353 ---------GFENYE-EVNEKYRSDSKEGKIEFDNVKNATQI------MLIQIRTRVNKILKKNI 401

  Fly   441 PVYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYR--NIERTVG 503
            |.|.|.|.:.                 |..:|.|||   |..:......::..|.:  |..|:
 Worm   402 PAYHYEYAYP-----------------KHANHTDDL---FFIMGVHPFIQDENEIKLGNFYRS-- 444

  Fly   504 IWTQFAATGNP-------------YSEKINGMDTLTIDPVRKSDEVIKCLN------ISDD---- 545
            ::..|..||||             |.| :|..:|....||.|::...|.|:      |..|
 Worm   445 MFLNFIKTGNPGNGCDGANLNGSTYFE-VNWNETTGERPVMKNNFEQKILDYWTKNMIEFDREVS 508

  Fly   546 -LKFIDLPEWPKLKVWESLY 564
             |:.|.....|..:|:.:.|
 Worm   509 LLRNIKSRRQPASRVFSAYY 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	119/529 (22%)
		Aes	<116..>221	CDD:223730	27/113 (24%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	130/575 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740