Protein Alignment alpha-Est7 and cest-25

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 151/510 - (29%)
• Similarity: 235/510 - (46%)
• Gaps: 65/510 - (12%)

  Fly    37 TEYGQVRGIKRLSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQPKDKAVQVQFV 101
            |.||.:.|.:.:...:....:|:|||||.||:|.|||..||....|..||:......:.:|...|
 Worm    21 TSYGPIEGRRLIHEGEKQVDAFQGIPYAAPPIGNLRFALPQPHEKWTEVRETKSFGARGIQKDHV 85

  Fly   102 FDKVEG--SEDCLYLNVYTN--NVKPDKARPVMVWIHGGGFIIGEANREWYGP----DYFMKEDV 158
            ......  |||.|.||::|.  ..|.:...||:::||||||:...|::  ||.    .:.:.:||
 Worm    86 LSPKTSPQSEDNLTLNIFTPVWTPKNETGFPVILYIHGGGFVSDSAHK--YGDMSICQHLVTKDV 148

  Fly   159 VLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGAS 223
            |:||||||||.|||.:  :.:.::|.|..|.|.|.||||:|.|...|.||||.||:.|:||||||
 Worm   149 VVVTIQYRLGFLGFWT--TGDSSIPDNVALHDMVFALKWVKENIGLFNGDPNNITLMGQSAGGAS 211

  Fly   224 THYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGYKGEDNDKDVLEFLQNVKA 288
            ..::.::..::.||.:.|...|:|.|.||.:....:.....|:.:|.....|..|.:|.|:.:.|
 Worm   212 VDFLSISPVSRDLFQKVIPMGGNASCSWAIHPRPLNACRNRAQEIGVFDGMNTLDWVEKLRELPA 276

  Fly   289 KDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKEMMKTAWSNSIPMFIGNTSYEG 353
             |......|:..::.:.:..:. .||..:....|     :|..|:.|.|...  |..:|....||
 Worm   277 -DKFASALNMEAVDTKTDPELL-IGPKYDNLFIP-----RPVMELRKEAPMK--PRLLGCAKSEG 332

  Fly   354 LLW--------------------VPEVKLMPQVLQQLDAGTPFIPKEL-LATEPSKEKLDSWSAQ 397
            |::                    :...||.|  |:..|.....:.|.: :.|:.|||:   |...
 Worm   333 LVFAFFGLNTKHPLHAVQQDVSAILSEKLFP--LKARDYQEKALEKLIEIGTDHSKEE---WQRA 392

  Fly   398 IRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAGAPVYFYRYDFDSEELIFPYRIMR 462
            :.|:       ..|::::: .|...|...|....|       .|:|.|.:|:.:.:   .|.||.
 Worm   393 MVDL-------KGDSFLNV-GIQQNVLDVLETQPS-------TPIYMYSFDYCNPK---AYGIMG 439

  Fly   463 LGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVGIWTQFAATGNPYSE 517
            .....|..:|..|:||...:.:.........:|:.||.|..:||.||..|||..|
 Worm   440 FKLPFKDATHCTDISYVVGNHIVNSFDFNEEDYKMIEITTRLWTNFAKYGNPNGE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	148/505 (29%)
		Aes	<116..>221	CDD:223730	48/110 (44%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	151/510 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.710