Protein Alignment alpha-Est7 and Ces1e

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Alignment Length: 592
• Identity: 174/592 - (29%)
• Similarity: 258/592 - (43%)
• Gaps: 145/592 - (24%)

  Fly    34 VADTEYGQVRGIKRLSL--YDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRD-------CS 89
            :.||..|:|.| |.:||  :..|...|.|:|:|:||:|.|||..||...||..|::       |.
Mouse    26 MVDTVQGKVLG-KYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCF 89

  Fly    90 QP--------------KDKAVQVQFVFDKVEGSEDCLYLNVYT--NNVKPDKARPVMVWIHGGGF 138
            |.              |:| :.:||       ||||||||:||  :..|.|:. ||||||||||.
Mouse    90 QDPVTGQIVNDLLTNRKEK-IPLQF-------SEDCLYLNIYTPADLTKSDRL-PVMVWIHGGGL 145

  Fly   139 IIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCA 203
            ::|.|: .:.|......|:||:|.||||||..||.|  :.:.:..||.|..|||.||.|:::|.|
Mouse   146 VLGGAS-TYDGLVLSTHENVVVVVIQYRLGIWGFFS--TGDEHSRGNWGHLDQVAALHWVQDNIA 207

  Fly   204 SFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLV 268
            .|||||..:|:|||||||.|...::|:...:.||.|.|.:||.|:..    |.:..|...:|:.:
Mouse   208 KFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESGVALTA----GLVKKNTRPLAEKI 268

  Fly   269 GYKGEDNDKDVLEFLQNVKAKDLI-----RVEENVL--TLEERMNKIMFAFGPSLE-----PFST 321
            .         |:...:|..:..::     :.||.:|  ||:..:.|:.. .|.|.:     |...
Mouse   269 A---------VISGCKNTTSAAMVHCLRQKTEEELLGTTLKLNLFKLDL-HGDSRQSHPFVPTVL 323

  Fly   322 PECVISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWV---------PEVKLMPQVLQQLDAGTPF- 376
            ...::.|.|:|::.....|::|..:|....| ..|:         .:|||.......|...:.|
Mouse   324 DGVLLPKMPEEILAEKNFNTVPYIVGINKQE-FGWILPTMMNYPPSDVKLDQMTAMSLLKKSSFL 387

  Fly   377 --IPKELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAG 439
              :|::.:|....|        .:||...||...  |..::|.....|..|:  |:.||....||
Mouse   388 LNLPEDAIAVAIEK--------YLRDKDYTGRNK--DQLLELIGDVVFGVPS--VIVSRGHRDAG 440

  Fly   440 APVYFYRY----DFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIER 500
            ||.|.|.:    .|.||  :.|..::.        .|.|::...|.:.:.|  ...|.|..|:.:
Mouse   441 APTYMYEFQYSPSFSSE--MKPDTVVG--------DHGDEIYSVFGAPILR--GGTSEEEINLSK 493

  Fly   501 -TVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWPKLKVWESLY 564
             .:..|..||..|||     ||.                           .||.||:       |
Mouse   494 MMMKFWANFARNGNP-----NGQ---------------------------GLPHWPE-------Y 519

  Fly   565 DDNKDLL 571
            |..:..|
Mouse   520 DQKEGYL 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	163/533 (31%)
		Aes	<116..>221	CDD:223730	52/106 (49%)
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	174/592 (29%)
		Aes	44..>242	CDD:223730	87/209 (42%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650