Protein Alignment alpha-Est7 and ache

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_571921.1
• Gene: ache / 114549
• ZFINID: ZDB-GENE-010906-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 659
• Identity: 185/659 - (28%)
• Similarity: 277/659 - (42%)
• Gaps: 175/659 - (26%)

  Fly    25 YRQSTNETVVADTEYGQVRGIKRLSLYDVPY-FSFEGIPYAQPPVGELRFKAPQRPIPWERVRDC 88
            :.|:..:.||| |..|:|:| .||.:.|..: .:|.|||||:||:|:.|||..:...||..|.:.
Zfish    22 FAQAEPDLVVA-TRLGRVQG-TRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEA 84

  Fly    89 SQPKDKAVQVQFVFDKVEG-------------SEDCLYLNVYTNNVKPDKARP----VMVWIHGG 136
            .:..:..  .|||.....|             |||||||||:.    |...||    |||||:||
Zfish    85 KEFSNAC--YQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWV----PPTPRPQNLTVMVWIYGG 143

  Fly   137 GFIIGEANREWYGPDYF-MKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKN 200
            ||..|.::.:.|...|. ..|.||:|::.||:||.||::|.... :.|||.||.||.|||:|::.
Zfish   144 GFYSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSS-DAPGNVGLYDQRLALQWVQE 207

  Fly   201 NCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYR-- 263
            |...|||:|..:|:||||||.||....:|:..::.||.|.|||||....|||   .:|.:..|
Zfish   208 NIHFFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWA---TVTFDEARRR 269

  Fly   264 ---IAKLVGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPF---STP 322
               :.||||... .||.::::.|:|...::||..|..||...   :...|:|.|.::..   .||
Zfish   270 TTKLGKLVGCTW-GNDTELIDCLRNKHPQELIDQEWQVLPWS---SLFRFSFVPVVDGVFFPDTP 330

  Fly   323 ECVISKPPKEMMKTAWSNSIPMFIGNTSY-EGLLWVPEVKLMPQVLQQLDAGTPFI--------- 377
            :.:||.                  ||..| :.||.|.:           |.|:.|:
Zfish   331 DAMISS------------------GNFKYTQILLGVNQ-----------DEGSYFLLYGAPGFSK 366

  Fly   378 -PKELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMD-----------------------LCS 418
             .:.|::.|...|.:........|:   |.|:....|.|                       :|.
Zfish   367 DNESLISREDFLESVKMGVPHANDI---GLEAVILQYTDWMDENNGQKNRDAMDDIVGDQNVICP 428

  Fly   419 IYYFV--FPALRVVHSRHAYAA--------------------GAPVYFYRYDFDSEELIFPYRIM 461
            :.:|.  :.....:|::.:.||                    || ||.|.:|..:..|.:|..:
Zfish   429 LQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSGNSHGA-VYLYLFDHRASNLAWPEWM- 491

  Fly   462 RLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVGIWTQFAATGNPYSEKINGMDT-- 524
                   ||.|..::.:.|...|.:||...:.|.:...|.:..|..||.||||.......||:
Zfish   492 -------GVIHGYEIEFVFGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGNPNVNTDGTMDSRR 549

  Fly   525 --------------LTIDP--VRKSDEVIKC----------LNISDDLK------FIDLPEWPKL 557
                          |..:|  |.|......|          |||:|::.      .::...|...
Zfish   550 RWPQFSANEQKHVGLNTEPMKVHKGLRTQFCALWNRFLPRLLNITDNIDDVERQWKVEFHRWSSY 614

  Fly   558 KV-WESLYD 565
            .: |:|.:|
Zfish   615 MMHWKSQFD 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	168/569 (30%)
		Aes	<116..>221	CDD:223730	49/109 (45%)
ache	NP_571921.1	COesterase	23..583	CDD:278561	177/616 (29%)
		AChE_tetra	598..631	CDD:285837	4/26 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575605
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740