Protein Alignment alpha-Est7 and Ache

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 556
• Identity: 171/556 - (30%)
• Similarity: 249/556 - (44%)
• Gaps: 109/556 - (19%)

  Fly    40 GQVRGIKRLSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQPKDKAVQ-VQFVFD 103
            ||:||| ||.....|..:|.|||:|:||||..||..|:...||..|.|.:..::...| |..::.
Mouse    46 GQLRGI-RLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYP 109

  Fly   104 KVEG----------SEDCLYLNVYTNNVKPDKARPVMVWIHGGGFIIGEANREWYGPDYFMK-ED 157
            ..||          |||||||||:|...:|....||::||:||||..|.|:.:.|...:..: |.
Mouse   110 GFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEG 174

  Fly   158 VVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGA 222
            .|||::.||:|..||::|.... ..|||.||.||.|||:|::.|.|:|||||..:|:||||||.|
Mouse   175 AVLVSMNYRVGTFGFLALPGSR-EAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAA 238

  Fly   223 STHYMMLTDQTQGLFHRGILQSGSAICPWA--YNGDITHNPYRIAKLVGYK---GEDNDKDVLEF 282
            |....:|:..::.||||.:||||:...|||  ..|:.......:|:|||..   ...||.:::..
Mouse   239 SVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIAC 303

  Fly   283 LQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLE-PFSTPECVISKPPKEMMKTAWSNSIPMFI 346
            |:...|:||:..|.:||..|   :...|:|.|.:: .|      :|..|:.::.|.....:.:.:
Mouse   304 LRTRPAQDLVDHEWHVLPQE---SIFRFSFVPVVDGDF------LSDTPEALINTGDFQDLQVLV 359

  Fly   347 GNTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLATEPSKEKLDSWSAQIRDVHRTGSESTPD 411
            |....||..:             |..|.|...|:       .|.|.| .||.....|.|.....|
Mouse   360 GVVKDEGSYF-------------LVYGVPGFSKD-------NESLIS-RAQFLAGVRIGVPQASD 403

  Fly   412 NYMDLCSIYY--FVFP--------ALRVVHSRH------------AYAAGAPVYFYRYDFDSEEL 454
            ...:...::|  ::.|        |:..|...|            ..|.||.||.|.::..:..|
Mouse   404 LAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTL 468

  Fly   455 IFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVGIWTQFAATGNPYSEKI 519
            .:|..:        ||.|..::.:.|...|...|...:.|....:|.:..||.||.||:|.
Mouse   469 TWPLWM--------GVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPN---- 521

  Fly   520 NGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWP 555
                    || |.|..                |:||
Mouse   522 --------DP-RDSKS----------------PQWP 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	163/513 (32%)
		Aes	<116..>221	CDD:223730	48/105 (46%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	171/556 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740