Protein Alignment alpha-Est7 and ache

DIOPT Version :10

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_002940088.1
• Gene: ache / 100490673
• XenbaseID: XB-GENE-923160
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 616
• Identity: 168/616 - (27%)
• Similarity: 260/616 - (42%)
• Gaps: 138/616 - (22%)

  Fly    33 VVADTEYGQVRGIKR--LSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQPKDKA 95
            ::..|..|:|||:::  ||.:   ..:|.|||:|:|||.::||:..:...||..|.|.:...:..
 Frog    29 LLVSTRSGKVRGLRQPVLSTH---VSAFLGIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPNAC 90

  Fly    96 VQVQFVFDKV--------------EGSEDCLYLNVYTNNVKPDKARPVMVWIHGGGFIIGEANRE 146
            .|   .||.:              ..||||||||::..:.:|..| .|||||:||||..|.::.:
 Frog    91 YQ---YFDTLYPGFPGMEMWNPNRPMSEDCLYLNIWVPHPRPSNA-TVMVWIYGGGFYSGSSSLD 151

  Fly   147 WYGPDYFM-KEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPN 210
            .|...|.. .|:|::|::.||:||.||::|....::.|||.||.||.|||:|:::|.|.|||||.
 Frog   152 VYDGRYLCHAENVIVVSMNYRVGAFGFLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPR 216

  Fly   211 CITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGYKGE-- 273
            .:|:||||||..|....:|:..:..||.:..|||||...|||     |..|....:.....|:
 Frog   217 TVTIFGESAGAVSVGMHVLSPGSHHLFSKAALQSGSPNTPWA-----TITPQEARRRTELLGKFL 276

  Fly   274 ----DNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKEMM 334
                .||.::|..|:..:.::||..|.:||...   :...|||.|..:....||     ||:.:|
 Frog   277 DCRMGNDTELLNCLRVKQPQELIDHEFSVLPAP---SVFRFAFVPVPDADFFPE-----PPEILM 333

  Fly   335 KTAWSNSIPMFIGNTSYEG---LLWVPEVKLMPQVLQQLDAGTPFIPK--ELLATEPSKEKLDSW 394
            ........|:.:|....||   ||:                |.|...|  |.|.|.  :|.|...
 Frog   334 NMGRFKPCPLIMGVNQNEGSYFLLY----------------GAPGFSKNNESLITR--EEFLGGV 380

  Fly   395 SAQIRDVHRTGSESTPDNYMD-----------------------LCSIYYFVFPALRVVHSRHAY 436
            ...:...:....|:....|.|                       :|.:.||   |.:|..:
 Frog   381 KMSVPQANDIALEAVVMQYTDWADEHAGVKNREAMDQLVGDHNVICPLTYF---AGKVAET---- 438

  Fly   437 AAGAPVYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERT 501
              |..||.|.:|..:..|.:|..:        ||.|..::.:.|...|...|....:|.....|.
 Frog   439 --GNRVYTYFFDHRASNLAWPQWM--------GVPHGYEIEFVFGLPLDANLNYTPQEEALSRRM 493

  Fly   502 VGIWTQFAATGNP-------------YSEKINGMDTLTIDPVRKSDEV------------IKCLN 541
            :..|..||.||:|             |:........|...|.::...:            .|.||
 Frog   494 MRYWANFARTGDPNEGNDAHQPRWPLYTASEQRYMALNNKPYQELQGIRVQTCMFWNRFLPKLLN 558

  Fly   542 ISDDLK------FIDLPEWPKLKV-WESLYD 565
            |:|::.      .::...|....: |::.:|
 Frog   559 ITDNIDEAERQWKVEFHRWSTYMMRWKNQFD 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	34..514	CDD:395084	156/530 (29%)
ache	XP_002940088.1	COesterase	31..549	CDD:395084	160/572 (28%)
		AChE_tetra	564..597	CDD:430146	3/26 (12%)