Protein Alignment alpha-Est7 and nlgn4x

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 655
• Identity: 167/655 - (25%)
• Similarity: 265/655 - (40%)
• Gaps: 169/655 - (25%)

  Fly     1 MNKNLGFVERLRW------RLKTIEHKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDV--PYFS 57
            :|.||     |.|      |...::.:.|.        .:..|.||::||.:.....::  |...
 Frog    21 VNSNL-----LLWIAALAVRFTIVDCQAQH--------PIVPTNYGKIRGTRTPLPIEILGPVEQ 72

  Fly    58 FEGIPYAQPPVGELRFKAPQRPIPWERVRD-------CSQPKDKA----------------VQVQ 99
            :.|:|||.||.||.||:.|:.|..|..:::       |.|..|:.                ..|.
 Frog    73 YLGVPYASPPTGERRFQPPEPPSSWTGIKNATQFAPVCPQFLDERSLLNDMLPIWFTANLDTVVS 137

  Fly   100 FVFDKVEGSEDCLYLNVY----------------TNNVK--------PDKARPVMVWIHGGGFII 140
            :|.|:   :|||||||:|                .||.:        |:..:||||:||||.::.
 Frog   138 YVQDQ---NEDCLYLNIYVPTEDGATTKKQADDIANNDRGEDEDIHDPNNKKPVMVYIHGGSYME 199

  Fly   141 GEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASF 205
            |..|. ..|.......:|:::|:.||||.|||:|  :.:....||.||.||:.||:||:.|..:|
 Frog   200 GTGNM-IDGSILASHGNVIVITVNYRLGVLGFLS--TGDQAAKGNYGLLDQIQALRWIEENIGAF 261

  Fly   206 GGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGY 270
            ||||..:|:||..||.:....:.|:..::|||.:.|:|||:|:..||.|    :.|.:..:::..
 Frog   262 GGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVN----YQPAKYTRILAD 322

  Fly   271 K-GED--NDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKE 332
            | |.|  :..|::|.|::...|:||:......|..       .||||.::     ..||...|:.
 Frog   323 KVGCDMLDTIDLVECLRDKNYKELIQQSITPATYH-------IAFGPVID-----GDVIPDDPQI 375

  Fly   333 MMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQV-------LQQLDAGTPFIPKELLATEPSKEK 390
            :|:.....:..:.:|....|||.:|..:     |       |...|.........|......|:.
 Frog   376 LMEQGEFLNYDIMLGVNQGEGLKFVDGM-----VDNEDGVSLSDFDFSVSNFVDNLYGYPEGKDT 435

  Fly   391 L--------DSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRV--VHSRHAYAAGAPVYFY 445
            |        ..|:      .:...|:.....:.|.:.:.:|.||:..  :|:|:    |:|.|||
 Frog   436 LRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHARY----GSPTYFY 490

  Fly   446 RYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQF-------SSLLARRLPKESREYRNIERTVG 503
            .:....:..:.|        .....:|.|::.|.|       :.|......|.......:..|
 Frog   491 AFYHHCQSEMKP--------TWADSAHGDEVPYVFGIPMIGPTELFNCNFSKNDVMLSAVVMT-- 545

  Fly   504 IWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDL-PEWPKLKVWESLYDDN 567
            .||.||.||:|...                        :..|.|||.. |...:...| |.||.
 Frog   546 YWTNFAKTGDPNKP------------------------VPQDTKFIHTKPNRFEEVAW-SKYDP- 584

  Fly   568 KDLLF 572
            ||.|:
 Frog   585 KDQLY 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	147/562 (26%)
		Aes	<116..>221	CDD:223730	45/128 (35%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:365897	160/617 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910