Protein Alignment alpha-Est7 and nlgn2b

DIOPT Version :10

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 643
• Identity: 167/643 - (25%)
• Similarity: 273/643 - (42%)
• Gaps: 161/643 - (25%)

  Fly     5 LGFVERL------RWRLKTIEHKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDV--PYFSFEGI 61
            ||...||      |..|.|.:|.            :..|.||::||:::....::  |...:.|:
Zfish    30 LGLALRLALSSCQRADLTTAKHP------------MVTTGYGKLRGVRKELNNEILGPVEQYLGV 82

  Fly    62 PYAQPPVGELRFKAPQRPIPWERVRDCSQ-----PK-------DKAVQVQFVFDKVEG------- 107
            |||.|||||.||:.|:.|..|:.:|:.:|     |:       :..:.|.|. |.::.
Zfish    83 PYATPPVGERRFQPPEAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFT-DNLDAAAAYVQN 146

  Fly   108 -SEDCLYLNVYT---------------------NNVKPDKARPVMVWIHGGGFIIGEANR----- 145
             ||||||||||.                     .:::..:.:|||::||||.|:.|..|.
Zfish   147 QSEDCLYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGTGNMFDASV 211

  Fly   146 -EWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDP 209
             ..||       :|::||:.||||.|||:|  |.:.:..||.||.||:.||:|:..|...|||||
Zfish   212 LAAYG-------NVIVVTMNYRLGVLGFLS--SGDQSAKGNYGLLDQIQALRWLNENIGHFGGDP 267

  Fly   210 NCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYR-------IAKL 267
            ..||:||..||.:..:.::|:..::|||.|.|.||||||..|:.|       ||       :||.
Zfish   268 ERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVN-------YRPLMYTKILAKK 325

  Fly   268 VGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKE 332
            ||....|. .|:::.|:....::|  |:::|     :..:...||||.::....|:     .|:.
Zfish   326 VGCSYSDT-ADLVDCLRRKSYREL--VDQDV-----QPARYHIAFGPVVDGDVVPD-----DPEI 377

  Fly   333 MMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAG----------TPFIP--------K 379
            :|:.....:..:.:|....|||.:|.:        .:.:.|          :.|:.        |
Zfish   378 LMQQGEFLNYDILLGVNQGEGLKFVDD--------NEGEEGISAASFDYTISNFVDNLYGYPEGK 434

  Fly   380 ELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRV--VHSRHAYAAGAPV 442
            ::| .|..|.....|:      .|...:......:.|.:.:.:|.||:..  :|:...    :||
Zfish   435 DIL-RETIKFMYTDWA------DRDNGDMRRKTLLALFTDHQWVAPAVATAKLHAEFQ----SPV 488

  Fly   443 YFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQF-------SSLLARRLPKESREYRNIER 500
            |||.:....:....|        .....:|.|::.|.|       :.|......|.......:..
Zfish   489 YFYTFHHHCQTEARP--------EWADAAHGDEIPYVFGVPMVGATELFPCNFSKNDIMLSAVVM 545

  Fly   501 TVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWPKLK 558
            |  .||.||.||:|..........:...| .:.:|||.....|.|.:::.:...|:::
Zfish   546 T--YWTNFAKTGDPNIPVPQDTKFIHTKP-NRFEEVIWTKFSSKDKQYLHIGLKPRIR 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	34..514	CDD:395084	151/562 (27%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	159/621 (26%)