DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc84D and UBE2L3

DIOPT Version :9

Sequence 1:	NP_524260.1	Gene:	Ubc84D / 40900	FlyBaseID:	FBgn0017456	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	NP_001243284.1	Gene:	UBE2L3 / 7332	HGNCID:	12488	Length:	212	Species:	Homo sapiens

Alignment Length:	154	Identity:	94/154 - (61%)
Similarity:	122/154 - (79%)	Gaps:	2/154 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAATRRL--TRELSDLVEAKMSTLRNIESSDESLLMWTGLLVPEKAPYNKGAFRIEINFPPQYPF 63
            :|..||.  ..||.::.:..|...|||:..:.:||.|.||:||:..||:|||||||||||.:|||
Human    57 LAGYRRAHGPEELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPF 121

  Fly    64 MPPKILFKTKIYHPNVDEKGEVCLPIISTDNWKPTTRTEQVLQALVAIVHNPEPEHPLRSDLAEE 128
            .||||.|||||||||:||||:||||:||.:||||.|:|:||:|:|:|:|::|:||||||:|||||
Human   122 KPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE 186

  Fly   129 FVREHKKFMKTAEEFTKKNAEKRP 152
            :.::.|||.|.|||||||..||||
Human   187 YSKDRKKFCKNAEEFTKKYGEKRP 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc84D	NP_524260.1	COG5078	1..150	CDD:227410	90/150 (60%)
Ubc84D	NP_524260.1	UBCc	6..149	CDD:214562	88/144 (61%)
UBE2L3	NP_001243284.1	COG5078	67..208	CDD:227410	87/140 (62%)
UBE2L3	NP_001243284.1	UBCc	67..207	CDD:214562	87/139 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0422
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51868
OrthoDB	1	1.010	-	-		D1420213at2759
OrthoFinder	1	1.000	-	-		FOG0002530
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106294
Panther	1	1.100	-	-	O	PTHR24068
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2225
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.790