Protein Alignment ARRB2 and Arr1

DIOPT Version :10

• Sequence 1: XP_011522160.1
• Gene: ARRB2 / 409
• HGNCID: 712
• Length: 440
• Species: Homo sapiens
• Sequence 2: NP_476681.1
• Gene: Arr1 / 35078
• FlyBaseID: FBgn0000120
• Length: 364
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 152/346 - (43%)
• Similarity: 234/346 - (67%)
• Gaps: 5/346 - (1%)

Human    39 RVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLK-DRKVFVTLTCAFRYGREDLDV 102
            :||||.|||..:|:|:.:|||||.:.:|:|:||::::|.:|:: :||:||.|.|.|||||||.::
  Fly     6 KVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEM 70

Human   103 LGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPED 167
            :||.|:|:|.:.:.|..||.....: .|::|:|||:|||.:|:||...:|.:.|.||.||....|
  Fly    71 IGLRFQKELTLVSQQVCPPQKQDIQ-LTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASD 134

Human   168 TGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLE 232
            ..:.|||.:.::.|...|..::||:|:::.|.|||||:||.|.|.||.....:.||:|...|.||
  Fly   135 ESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELELE 199

Human   233 ASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQLEQDD--QVS 295
            .:|||:||:|||.::||:.|.|||.|.|||||..|:|..|:.||...|::..:|.:|..:  .::
  Fly   200 VTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPLN 264

Human   296 PSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLV 360
            |.|:..||..:.|.|..|.::.|:|::|.:|.:||.|||:|::.....::..||:|||.|||||.
  Fly   265 PGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKLF 329

Human   361 V-SRGGDVSVELPFVLMHPKP 380
            : :.||::..||||:||||||
  Fly   330 LGALGGELCAELPFILMHPKP 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARRB2	XP_011522160.1	Arrestin_N	50..206	CDD:451447	66/156 (42%)
		Arrestin_C	225..380	CDD:214976	69/157 (44%)
Arr1	NP_476681.1	Arrestin_N	17..173	CDD:451447	66/156 (42%)
		Arrestin_C	192..350	CDD:214976	69/157 (44%)