Protein Alignment alpha-Est8 and ces2.4

DIOPT Version :10

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001072187.1
• Gene: ces2.4 / 779633
• XenbaseID: XB-GENE-5765838
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 579
• Identity: 167/579 - (28%)
• Similarity: 238/579 - (41%)
• Gaps: 132/579 - (22%)

  Fly    46 KWQSIYGNN---------YYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQVNIV 101
            |:..:.||.         .:.|.|:||||||:|.|||:||..||.||.|:..|  .|.|    :.
 Frog    30 KYGQLLGNTVGAKETDRLVHVFMGVPFAKPPIGPLRFEAPQPPEPWSSVREAT--AAPP----MC 88

  Fly   102 LKQVQG-----------------SEDCLYLNVYTRELHPHRP-LPVLVWIYGGGFQMGEASRDLY 148
            |:..:|                 |||||||||:|.......| |||:|:|:|||..||.|.. ..
 Frog    89 LQDKRGMEALAKYFKAEFDFPPVSEDCLYLNVFTPADRGENPELPVMVFIHGGGLTMGGAFM-FE 152

  Fly   149 SPDYIMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNIT 213
            .......|:||:|.|.||||.:||.|..|:|  |.||.|..|||.||:||:.|.:.|||:|.::|
 Frog   153 GTALCAYENVVVVSIQYRLGIMGFFSSGDKE--VRGNFGFLDQVAALQWVRDNIKDFGGNPQSVT 215

  Fly   214 VFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDR- 277
            :|||||||.|....:|:..:||||||.|..||.|:.|                  |:.....:.
 Frog   216 IFGESAGGGSVSAQVLSPLSKGLFHKAIAESGVAIIP------------------GFMSSKTEEI 262

  Fly   278 ----DIFAHLKKCKASSML----KVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEM 334
                .:.|::..|..|.::    |..||.|.......:..||       |.:.....:||...|:
 Frog   263 LPVLSVVANISSCSVSELVGCLKKKTEDEIVAITAAMKFVMF-------PAVVDGVFLPKPAEEI 320

  Fly   335 MRDCWGNSIPMVIGGNSFE-GLLMFPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFGKK--- 395
            :.....|.:|.:||.|:.| |.::       |......|..|.:..:|............|.
 Frog   321 LAAKESNPVPFLIGINNHEFGWML-------PVAFNLTGYREGMEKKDIQAILGTLPLLNKVPFV 378

  Fly   396 ---VRELYFGDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDF------D 451
               :.|.||||....::....:.||.....|.....||  ::.|.....|.:.|.|..      |
 Frog   379 IPFIMEEYFGDTDEPKELRNNFLDLAGDTIFVIPALRT--AKYHRDSGFPVYFYEFQHRPSMFAD 441

  Fly   452 SKHFNIMRIITCGRKVRGTCHADDLSYL----FYNAAAKKLKRRTAEFKTI-KRLVSMVVHFAIS 511
            ||...:.           ..|.|:|.::    |..:........|.|.|.: |.::....:||.:
 Frog   442 SKDDFVK-----------ADHGDELYFVGGGPFLKSVLLFKSNATEEEKILSKTIMKYWANFARN 495

  Fly   512 GDPN------IPMVCQDEKEQPRGAWLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLW 564
            ||||      .|...:||.      :|.|:...|..|.|            :..:|:.|
 Frog   496 GDPNGLGLAEWPKYDEDED------YLEINLTQKSSQRL------------KGGRLKFW 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	34..564	CDD:395084	166/577 (29%)
ces2.4	NP_001072187.1	COesterase	25..536	CDD:395084	166/577 (29%)