Protein Alignment alpha-Est8 and Ces5a

DIOPT Version :10

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 522
• Identity: 161/522 - (30%)
• Similarity: 241/522 - (46%)
• Gaps: 82/522 - (15%)

  Fly    37 TVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKP--CQVN 99
            ||.|:::.|.          .|.|||||.||:|.|||..|..|..|.:::..|   |.|  |..|
Mouse    50 TVLGRLEPVN----------VFLGIPFAAPPLGPLRFSKPQPPIPWDNLREAT---AYPNLCFQN 101

  Fly   100 I--------VLK---QVQG-SEDCLYLNVYTRELHPHR--PLPVLVWIYGGGFQMGEASRDLYSP 150
            :        :||   .:.| ||||||||:|. ..|.:.  .|||:|||.||||:.|.||  ::..
Mouse   102 LEWLFIYQNLLKVSYPILGMSEDCLYLNIYA-PCHANNGSSLPVMVWIPGGGFETGSAS--IFDG 163

  Fly   151 DYI-MMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITV 214
            ..: :.|.|::|.|.||||..||.:..::.  .|||....||:.||.||:.|.::|||:||::|:
Mouse   164 SALAVYEDVLVVTIQYRLGIFGFFTTQNQH--APGNWAFWDQLAALLWVRENIKYFGGNPDSVTI 226

  Fly   215 FGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDI 279
            ||.|||..|...::|:..:..|||:.|:.||.|:.|..::..: :..:.| |......|.|..|.
Mouse   227 FGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDN-DLKHDL-QVVANVCDCNVSDS 289

  Fly   280 FAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIP 344
            .|.||..:..|.|    :::::.::.:..|....|          ....:.|||::.......:|
Mouse   290 KALLKCLREKSSL----ELMSLSQKAKSFTRVVDG----------SFFSEEPLELLSQKTLKIVP 340

  Fly   345 MVIGGNSFEGLLMFPEVNKWPELLCQLGDCEN----LAPQDAHVDEQQRKAFGKKVRELYFGDRT 405
            .:||.|:.|...:.| |...||:|  ||..|:    |.....|:..|......|   |.:.|..:
Mouse   341 SIIGVNNQECGYILP-VRDTPEIL--LGSNESTALTLIHTLLHIPTQHLYIVTK---EYFHGKHS 399

  Fly   406 PG--RKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVR 468
            |.  |.|:|   |||...:|  .:...:.:|.|.....|.:.|.|......|...|    ...|:
Mouse   400 PTDIRDTLL---DLFGDVFF--VVPGLVTARYHRDSGGPVYFYEFQHRPHCFQNSR----PAFVK 455

  Fly   469 GTCHADDLSYLFYNAAAK----KLKRRTAEFKTIKR-LVSMVVHFAISGDPN----IPMVCQDEK 524
            .. |.|::.::|.....|    ..:..|.|.|.:.| ::....:||.|||||    .|....||.
Mouse   456 AD-HTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPNGADLPPWPVYDEN 519

  Fly   525 EQ 526
            ||
Mouse   520 EQ 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	34..564	CDD:395084	161/522 (31%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	161/522 (31%)