Protein Alignment alpha-Est8 and nlgn3b

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 625
• Identity: 164/625 - (26%)
• Similarity: 259/625 - (41%)
• Gaps: 160/625 - (25%)

  Fly    36 DTVYGKVKG----VKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPC 96
            :|..|:::|    |..:.:...:.|.  |:|:|.|||||.||..|..|..||.|:..|  |..|.
Zfish    49 NTALGRLRGMRVAVATEGLGPVDQYL--GVPYAAPPVGEKRFMPPDAPSAWSGVRNAT--RFPPV 109

  Fly    97 QVNIVLKQV---------------------QGSEDCLYLNVY-------------------TRE- 120
            ....|...|                     :.||||||:|:|                   |.:
Zfish   110 CPQTVRNAVPDIMMPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKRTGDMSADTERTEDD 174

  Fly   121 -LHPHR--PLPVLVWIYGGGFQMGEASRDLYSPDYIMME--------HVVLVVISYRLGALGFLS 174
             |...|  |.||:::|:||.:..|..:         :|:        :|:::.::||:|.|||||
Zfish   175 GLRDSRDDPRPVMLFIHGGSYMEGTGN---------IMDGSVLASYGNVIVITLNYRVGILGFLS 230

  Fly   175 LADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHK 239
            ..|:.  ..||.||.||:.||||:.:|..:|||||..:||||...|.:....:.|:..::||||:
Zfish   231 TGDQA--AKGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHR 293

  Fly   240 TIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDIFAHLKKCKASSMLKVAEDIITMEER 304
            .||.|||||:.|:.....:.:...||:..|                |   ::|...:.::.|::|
Zfish   294 AIIQSGSALSSWSVNYQPVKYTRLLAERVG----------------C---NVLDTQDLVLCMQKR 339

  Fly   305 HQRLTM----------FSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGLLMFP 359
            ..|..:          .:|||.|:..|     ||..|..:|......:..:::|.|..|| ..|.
Zfish   340 SYRELVEQEIQPARFHVAFGPVIDGDL-----IPDDPEVLMEQGEFLNYDIMLGVNQGEG-FRFV 398

  Fly   360 EVNKWPELLCQLGDCENLAPQDAHVDE-----QQRKAFGKKVRELY--FGDR---TPGRKTILE- 413
            |....||.....|...:....| .||.     :.:....:.::.:|  :.||   ...|||::.
Zfish   399 EGVVEPEEGGVSGSDFDFTVSD-FVDSLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVAM 462

  Fly   414 YSDLFSYKYFWHGIHRTLLSRAHHAPL-APTFLYRFDFDSKHFNIMRIITCGRKVR----GTCHA 473
            ::|     :.|  :...:::...||.. :|||.|.|    .|.       |...::    .:.|.
Zfish   463 FTD-----HQW--VEPAVVTADLHARYGSPTFFYAF----YHH-------CQSPMKPPWADSAHG 509

  Fly   474 DDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVV-----HFAISGDPNIPMVCQDEK--------- 524
            |:|.|:|........:.....|.....::|.||     :||.:||||.| |.||.|
Zfish   510 DELPYVFGVPLIGPTELFPCNFSRNDIMLSAVVMTYWTNFAKTGDPNKP-VPQDTKFIHTKANRF 573

  Fly   525 EQPRGAWLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLW 564
            |:.  .|......|:::  |:|.....|.|...|.|:..|
Zfish   574 EEV--TWAKYGPHDQLY--LHIGLKPRVRDHYRATKVAFW 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	163/623 (26%)
		Aes	<116..>221	CDD:223730	42/135 (31%)
nlgn3b	XP_005165239.1	COesterase	40..609	CDD:278561	163/623 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740