Protein Alignment alpha-Est8 and ces2a

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 562
• Identity: 154/562 - (27%)
• Similarity: 235/562 - (41%)
• Gaps: 103/562 - (18%)

  Fly    34 IADTVYGKVKG----VKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTH---- 90
            :|...:|.|:|    .|........|.   |||||:||||..|..||...:.|..::..|.
Zfish    28 VAVLKHGSVRGQYVKAKGSPAVVEQYL---GIPFAQPPVGPHRLAAPQPVQGWEGIRNATEHPLM 89

  Fly    91 -------VRAKPCQVNIVLKQVQGSEDCLYLNVYT-RELHPHRPLPVLVWIYGGGFQMGEAS--R 145
                   :.|....:::.:..:..||||||||||| .:......|||::||:|||..||.|.  :
Zfish    90 CLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEKLPVMIWIHGGGLAMGGACMFK 154

  Fly   146 DLYSPD---YIMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGG 207
            :|...|   ....|.||:|||.||||.||:.|..|:.  ..||.|..||:.||:||::|.:.|||
Zfish   155 ELCLYDGTPLAAYEKVVVVVIQYRLGILGYFSTGDQH--AKGNWGFLDQIAALQWVQQNIEAFGG 217

  Fly   208 DPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGY-- 270
            ||.::|:.||||||.|...:.|:...||||.:.|..||                  :|...||
Zfish   218 DPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSG------------------VATVKGYFV 264

  Fly   271 TGDANDRDIFAHLKKCKASSMLKVAEDIITMEERH-----QRLTMFSFGPTIEPYLTPHCVIPKS 330
            ...:....:.|::.:|..||...:.:.|..|.|..     |:..:|. |..::...     |...
Zfish   265 KDPSTHAQVIANITECDFSSSEVLVKCIREMTEEQIIKAAQKKGIFP-GAAVDGEF-----IKAQ 323

  Fly   331 PLEMMRDCWGNSIPMVIGGNSFEGLLMFPEV---NKWPELLCQLGDCENLAPQDAHVDEQQRKAF 392
            |.|:::......:|::||..:.|...|.|::   .:|.:.:......:.|...:|   :....|.
Zfish   324 PEEILKSKDFQKVPILIGTTNHEFGWMLPQIFLPKEWVKGMDTKAAKDRLGLLNA---DGASGAN 385

  Fly   393 GKKVRELYFGDRTPG--RKTILE-YSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKH 454
            |....|.:...:||.  |....| ..|:|..      |....::..|.....|.::|.|......
Zfish   386 GIIADEYFKNAKTPEEIRDAFTELLGDIFMV------IPSITVASYHREAGVPVYMYEFQHGPST 444

  Fly   455 FNIMRIITCGRKVRGTC----HADDLSYL----FYNAAAKKLKRRTAEFKTIKRLVSMV-VHFAI 510
            .|         |.|.:.    ||||:.::    |::...|.|...|.|...:.|.|... .:|..
Zfish   445 AN---------KFRPSFVKADHADDVGFVFGACFWDVHVKGLGTLTEEENQLCRTVMKYRANFIR 500

  Fly   511 SGDPN---IPMVCQDEK--------EQPRGAWLPISKDDKVF 541
            :|.||   :|....|:.        :|..|.  .:.||..:|
Zfish   501 TGSPNPAPVPWPVYDQSNKYLNLGLQQTEGQ--DLKKDKLLF 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	154/562 (27%)
		Aes	<116..>221	CDD:223730	50/110 (45%)
ces2a	NP_001070720.1	COesterase	21..541	CDD:278561	154/562 (27%)
		Aes	<122..346	CDD:223730	80/249 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575352
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.830