Protein Alignment alpha-Est8 and nlgn3a

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 640
• Identity: 169/640 - (26%)
• Similarity: 263/640 - (41%)
• Gaps: 171/640 - (26%)

  Fly    36 DTVYGKVKGVK---WQSIYG--NNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKP 95
            :|.|||::|.:   ...|.|  :.|.   |:|:|.|||||.||..|..|..||.:|..||. |..
Zfish    72 NTQYGKLRGARVPLHSEILGPVDQYL---GVPYATPPVGEKRFLPPEPPSSWSGIKNATHF-APV 132

  Fly    96 CQVN-------------------IVLKQVQG-SEDCLYLNVY-------------TRELHPHRPL 127
            |..|                   ||...:|. :|||||||:|             ||:  |::.:
Zfish   133 CPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRK--PNKKI 195

  Fly   128 --------------------------------PVLVWIYGGGFQMGEASRDLYSPDYIMME---- 156
                                            ||:|:|:||.:..|..:         |::
Zfish   196 CRKGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEGTGN---------MIDGSVL 251

  Fly   157 ----HVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGE 217
                :|:::.:::|:|.|||||..|:.  ..||.||.||:.||||:..|..:||||.:.|||||.
Zfish   252 ASYGNVIVITLNFRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGS 314

  Fly   218 SAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDIFAH 282
            ..|.:....:.|:..::||||:.||.|||||:.||.....:.:...||:..|    .|..|....
Zfish   315 GIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWAVNYQPVKYTRLLAEKVG----CNVLDTLDM 375

  Fly   283 LKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVI 347
            :...:..|..::.|..|.....|     .:|||.|:     ..|||..|..:|......:..:::
Zfish   376 VDCLRKKSARELVEQDIQPARYH-----VAFGPVID-----GDVIPDDPEILMEQGEFLNYDIML 430

  Fly   348 GGNSFEGLLMFPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFG---------KKVRELY--F 401
            |.|..|||       ::.|.:....|..:....|..|.:.....:|         :.::.:|  :
Zfish   431 GVNQGEGL-------RFVENVVDSEDGVSGNDFDFSVSDFVDSLYGYPEGKDTLRETIKFMYTDW 488

  Fly   402 GDR---TPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPL-APTFLYRFDFDSKHFNIMRIIT 462
            .||   ...|||::.   ||: .:.|  :..::::...||.. :||:.|.|    .|.
Zfish   489 ADRDNPETRRKTLVA---LFT-DHQW--VEPSVVTADLHARYGSPTYFYAF----YHH------- 536

  Fly   463 CGRKVR----GTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVV-----HFAISGDPNIPM 518
            |...::    ...|.|::.|:|..............|.....::|.||     :||.:||||.|
Zfish   537 CQSLMKPAWSDAAHGDEVPYVFGIPMIGPTDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNKP- 600

  Fly   519 VCQDEK---------EQPRGAWLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLW 564
            |.||.|         |:.  ||...:..|:::  |:|.....|.|...|.|:..|
Zfish   601 VPQDTKFIHTKANRFEEV--AWSKYNPQDQLY--LHIGLKPRVRDHYRATKVAFW 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	168/638 (26%)
		Aes	<116..>221	CDD:223730	41/157 (26%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:306613	168/638 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575373
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840