Protein Alignment alpha-Est8 and ces2b

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_021326380.1
• Gene: ces2b / 561967
• ZFINID: ZDB-GENE-041014-96
• Length: 1611
• Species: Danio rerio
• Alignment Length: 588
• Identity: 172/588 - (29%)
• Similarity: 257/588 - (43%)
• Gaps: 134/588 - (22%)

  Fly    34 IADTVYGKVKG----VKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAK 94
            :.:|..|.::|    ||.:....|:|.   |:||||||||.||...|...|.|..|:..|. :.:
Zfish  1082 VVETKLGSLRGAFLTVKGKDTIVNSYL---GVPFAKPPVGPLRLARPQAAEKWQGVRDATK-QPR 1142

  Fly    95 PC--------------QVNIVLKQVQGSEDCLYLNVYTRELHPHRP------LPVLVWIYGGGFQ 139
            .|              .:::.:.:|  ||||||||:||    |.:|      |||:|||:|||..
Zfish  1143 MCLQERQMTVTELEFLSMDVEVPEV--SEDCLYLNIYT----PVKPGQGDKKLPVMVWIHGGGLS 1201

  Fly   140 MGEASRDLYSPDYI-MMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQ 203
            :|.||  :|....: ..:.||:|:|.||||.|||||..||.  .|||.|..|||.||:||:.|..
Zfish  1202 LGSAS--MYDGSVLAAYQDVVVVLIQYRLGLLGFLSTGDEH--APGNYGFLDQVAALQWVQENIH 1262

  Fly   204 FFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINW-------P 261
            .|||||.::|:|||||||.|...::|:..|.||||:.|..||:|.           |       |
Zfish  1263 SFGGDPGSVTIFGESAGGISVSTLILSPLASGLFHRAIAESGTAF-----------WDGLVMADP 1316

  Fly   262 YRLAQATGYTGDANDRDIFAHLKKCKASSMLKVAEDIITMEERH-----QRLTMFSFGPTIEPYL 321
            ::.||..            |....|.:||..|:.:.|:...|..     ::..|..|...::.|.
Zfish  1317 FQRAQTA------------AKQCNCDSSSSAKIVDCIMHWSEEEALECAKKFQMMHFSVAVDSYF 1369

  Fly   322 TPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGLLMFPEVNKWPELLC-----QLGDCENLA--- 378
                 :||...|::.....:.:|::.|.|:.|...:..|....||.:.     |:.:...|.
Zfish  1370 -----LPKPIEEIVEKQEFSKVPLINGINNDEFGFLLAEYFLGPEWMNGLKREQIAEALTLTYPD 1429

  Fly   379 PQDAH-VDEQQRKAFGK-----KVRELY---FGDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSR 434
            |:|.. :|...::..|.     ::||:|   .||            .||:       |....|::
Zfish  1430 PKDRWIIDLVAKEYLGDTHDPIEIREVYREMMGD------------VLFN-------IPALQLAK 1475

  Fly   435 AHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVR----GTCHADDLSYLFYNAAAKKLKRRTAEF 495
            .|....||.:||.........         :|.|    |..|||||.::.....||...|.:|.|
Zfish  1476 HHSGTGAPVYLYELQHPPSFL---------QKKRPSFVGVDHADDLYFIQGTCFAKAHLRISAPF 1531

  Fly   496 -----KTIKRLVSMVVHFAISGDPNIPMVCQDEKEQPRGAWLPISKDDKVFQCLNISH-DVHVID 554
                 :..:.:::...:||.:|.||.|.:....:.:....:|.|....|..:.|...| :.....
Zfish  1532 TEEENELCRTVMAYWGNFAHTGSPNGPGLTHWPEYENENEYLAIGLQQKPGKNLKHKHYEFMTKT 1596

  Fly   555 LPE 557
            |||
Zfish  1597 LPE 1599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	172/588 (29%)
		Aes	<116..>221	CDD:223730	55/111 (50%)
ces2b	XP_021326380.1	COesterase	27..539	CDD:306613
		COesterase	553..1065	CDD:306613
		COesterase	1079..1592	CDD:306613	169/579 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910