Protein Alignment alpha-Est8 and nlgn4xa

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_021330915.1
• Gene: nlgn4xa / 561122
• ZFINID: ZDB-GENE-100309-2
• Length: 844
• Species: Danio rerio
• Alignment Length: 616
• Identity: 166/616 - (26%)
• Similarity: 260/616 - (42%)
• Gaps: 139/616 - (22%)

  Fly    34 IADTVYGKVKGVKW---QSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKP 95
            |..|.|||::|:|.   ..|.| ....:.|||:|.||.||.||:.|..|..|..::..|.. |..
Zfish    44 IVTTNYGKLRGLKTPLPNEILG-PVEQYLGIPYALPPTGERRFQPPEPPMSWPGIRNATQF-APV 106

  Fly    96 C--------------------QVNIVLKQVQG-SEDCLYLNVY---------------------T 118
            |                    .::.|:..||. ||||||||:|                     .
Zfish   107 CPQFLEDRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDVGANKGDDFTNNEGGEN 171

  Fly   119 RELHPHRPL-PVLVWIYGGGFQMGEASRDLYSPDYIMME--------HVVLVVISYRLGALGFLS 174
            :::|....| ||:|:|:||.:..|..:         |::        :|::|.::||||.|||||
Zfish   172 KDIHDENGLRPVMVYIHGGSYMEGTGN---------MIDGSILASYGNVIVVTLNYRLGVLGFLS 227

  Fly   175 LADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHK 239
            ..|:.  ..||.||.||:.||||:|.|.|.|.|||..:|:||..||.:....:.|:..::.||.|
Zfish   228 TGDQA--AKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQK 290

  Fly   240 TIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDIFAHLKKCKASSMLKVAEDIITMEER 304
            .||.||:||:.||.......:...||:..|    .|..|....::..:..:..::.|..||..:.
Zfish   291 AIIQSGTALSSWAVNYQPAKYTRILAEKVG----CNMLDSIDLVECLQNKNYKELIEQYITQAKY 351

  Fly   305 HQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGLLMFPEVNKWPELLC 369
            |     .:|||.|:     ..|||..|..:|......:..:::|.|..||.       |:.:.:.
Zfish   352 H-----IAFGPVID-----GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGF-------KFVDGIV 399

  Fly   370 QLGDCENLAPQDAHVDEQQRKAFG---------KKVRELY--FGDR---TPGRKTILEYSDLFSY 420
            ...|..:....|..|.:.....:|         :.::.:|  :.|:   ...|||::.   ||:
Zfish   400 DSEDGVSANDFDFAVSDFVDHLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVA---LFT- 460

  Fly   421 KYFWHGIHRTLLSRAHHAPL-APTFLYRFDFDSKHFNIMRIITCGRKVR----GTCHADDLSYLF 480
            .:.|  :...:.:...||.. :||:.|.|    .|.       |..:::    .:.|.|::.|:|
Zfish   461 DHQW--VAPAVATADLHAQYGSPTYFYAF----YHH-------CQSEMKPSWSDSAHGDEVPYVF 512

  Fly   481 YNAAAKKLKRRTAEFKTIKRLVSMVV-----HFAISGDPNIPMVCQDEK---EQPRG----AWLP 533
            ..............|.....::|.||     :||.:||||.| |.||.|   .:|..    ||..
Zfish   513 GIPMLGPTDLFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQP-VPQDTKFIHTKPNRFEEVAWSK 576

  Fly   534 ISKDDKVFQCLNISHDVHVIDLPEAEKLRLW 564
            .:..|:::  |:|.....|.|...|.|:..|
Zfish   577 YNPKDQLY--LHIGLKPRVRDHYRATKVAFW 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	165/614 (27%)
		Aes	<116..>221	CDD:223730	44/134 (33%)
nlgn4xa	XP_021330915.1	COesterase	43..605	CDD:306613	165/614 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575655
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740