Protein Alignment alpha-Est8 and ces3

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 565
• Identity: 157/565 - (27%)
• Similarity: 228/565 - (40%)
• Gaps: 128/565 - (22%)

  Fly    39 YGKVKG----VKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQ-V 98
            :|.|:|    .|........|.   |||||:||||..|..||...:.|..::..|...:...| .
Zfish    33 HGSVRGQYVKAKGSPAVVEQYL---GIPFAQPPVGPHRLAAPQPVQGWEGIRNATEYSSMCLQDP 94

  Fly    99 NIVLKQVQG----------SEDCLYLNVYT-RELHPHRPLPVLVWIYGGGFQMGEASRDLYSPDY 152
            |||.|..:.          ||||||||||| .:.......||:|||:||...:|.|.....:| .
Zfish    95 NIVPKYAKSMTLELPPTGVSEDCLYLNVYTPSQRSESDKFPVMVWIHGGALVIGGACMYDGTP-L 158

  Fly   153 IMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGE 217
            ...|.||:|||.||||.||:||..|:.  ..||.|..||:.||:||::|.:.|||||.::|:.||
Zfish   159 AAYEKVVVVVIQYRLGILGYLSTGDQH--AQGNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGE 221

  Fly   218 SAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYT--GDANDRDIF 280
            ||||.|...:.|:...||||.:.|..||                  :|...||:  .......:.
Zfish   222 SAGGISASLLTLSPMTKGLFQRAIFQSG------------------VATVKGYSFKDPLTYAKVI 268

  Fly   281 AHLKKCKASS---MLK-----VAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRD 337
            |::.:|..||   ::|     ..|.||...::..||.    |.|::...     |...|.|:::.
Zfish   269 ANITECDFSSSEVLVKCIREMTEEQIIKAAQKKYRLP----GATVDGEF-----IKAQPEEILKS 324

  Fly   338 CWGNSIPMVIGGNSFE-GLLMFPEV--NKWPELLCQLGDCENLAPQ--DAHVDEQQRKAFGKKVR 397
            .....||:::|..:.| |..:...:  ..|.:     |.....|.|  |...:....:|.|....
Zfish   325 KDFPKIPILVGTTNHEFGWTLSHAILPKDWAK-----GMDAKSAKQTLDFFYNAGASEANGIIAD 384

  Fly   398 ELYFGDRTPGRKTILEYSDLF------------SYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDF 450
            |.:...:||.     |..|.|            |.|          ::..|....||.::|.|..
Zfish   385 EYFKNAKTPE-----EIRDAFTELLGDIIMVIPSIK----------VASYHRDAGAPVYMYEFQH 434

  Fly   451 DSKHFNIMRIITCGRKVRGTC----HADDLSYL----FYNAAAKKLKRRTAEFKTIKRLVSMV-V 506
            .....|         |.|.:.    |.|::.::    |::...|.....|.|...:.|.|... .
Zfish   435 GPSIAN---------KFRPSFVKADHGDEIGFMFGACFWDGQVKVTGTLTEEENQLCRTVMKYWA 490

  Fly   507 HFAISGDPN---IPMVCQDEK--------EQPRGAWLPISKDDKV 540
            :|..:|.||   :|....|:.        :|..|..|   |.||:
Zfish   491 NFVRTGSPNPAPVPWPVYDQSNKYLNLGLQQTEGQGL---KKDKL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	157/565 (28%)
		Aes	<116..>221	CDD:223730	48/105 (46%)
ces3	NP_001038401.1	COesterase	24..535	CDD:278561	157/565 (28%)
		Aes	<122..>235	CDD:223730	52/115 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840