Protein Alignment alpha-Est8 and Ces1b

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 577
• Identity: 176/577 - (30%)
• Similarity: 259/577 - (44%)
• Gaps: 100/577 - (17%)

  Fly    34 IADTVYGKVKGVKWQSIYGNNY--YSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKP- 95
            :.||..||:.| |:.|:.|..:  ..|.|:||||||:|.|||..|...|.||.||..|   :.|
Mouse    25 VVDTTQGKILG-KYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNAT---SYPP 85

  Fly    96 -CQVNIVLKQVQG--------------SEDCLYLNVYT-RELHPHRPLPVLVWIYGGGFQMGEAS 144
             |..:.|..|:..              ||||||||:|: .:|.....|||:|||:|||...|.||
Mouse    86 MCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTGGAS 150

  Fly   145 RDLYSPDYIMM-EHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGD 208
              ||:...:.. |:||:|.|.||||..|..|..||.  ..||....||:.|||||:.|...|||:
Mouse   151 --LYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEH--SRGNWAHLDQLAALRWVQDNIANFGGN 211

  Fly   209 PDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGD 273
            ||::||||.||||.|...::|:..||.|||:.|..|...|.....|...:  ...|:|.......
Mouse   212 PDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDLV--ACDLSQMIATVSG 274

  Fly   274 ANDRDIFAHLKKCKASSMLKVAEDIITME---------ERHQRLTMFSFGPTIEPYLTPHCVIPK 329
            .||....|.::..:..:..::.|..:.:|         .:....:|.:        :....|:||
Mouse   275 CNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSMST--------VIDGVVLPK 331

  Fly   330 SPLEMMRDCWGNSIPMVIGGNSFEGLLMFPEVNKWPELLCQLGD----------CENLAPQDAHV 384
            :|.|::.:...:::|.::|.|..|...:.|.:         |||          ..:|..:..|.
Mouse   332 APEEILAEKSFSTVPYIVGFNKQEFGWIIPTM---------LGDLLSEGKMNEETASLLLRRFHS 387

  Fly   385 DEQQRKAFGKKVRELYF-GDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRF 448
            |....::....|.|.|. |...|.:|..| ..|:||..:|  ||...||||:.......|::|.|
Mouse   388 DLNISESLIPAVIEKYLRGTDDPAKKRDL-LLDMFSDVFF--GIPAVLLSRSLRDAGVSTYMYEF 449

  Fly   449 DFDSKHFNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKT--IKRLVSMVVHFAIS 511
            .:.....:..|..|    |.|. |.|::..:|   ....||..|:|.:|  .|.::....:||.:
Mouse   450 RYRPSFVSDKRPQT----VEGD-HGDEIFSVF---GIPLLKEGTSEEETNLSKMVMKFWANFARN 506

  Fly   512 GDPN---IPMVCQ-DEKEQPRGAWLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLW 564
            |:||   :|...: ||||    .:|.|....:..|.|            :||::..|
Mouse   507 GNPNGEGLPHWPEYDEKE----GYLQIGATTQQAQRL------------KAEEVAFW 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	175/575 (30%)
		Aes	<116..>221	CDD:223730	50/106 (47%)
Ces1b	NP_001074841.1	COesterase	19..547	CDD:278561	175/575 (30%)
		Aes	<121..>239	CDD:223730	56/121 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740