Protein Alignment alpha-Est8 and Ces2i

DIOPT Version :10

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_008758816.2
• Gene: Ces2i / 292152
• RGDID: 1565045
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 169/610 - (27%)
• Similarity: 260/610 - (42%)
• Gaps: 164/610 - (26%)

  Fly    25 QRLRSNDKV--IADTVYGKVKG----VKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWS 83
            |.:...|..  |.:|..|:|:|    ||...   :..::|.||||||||||.|.|..|.:||.||
  Rat    22 QHVHGQDSASPIRNTQTGQVRGSFVHVKDTK---SGVHTFLGIPFAKPPVGPLHFAPPEDPEPWS 83

  Fly    84 DVKRCTHVRAKPCQVNIV----LKQVQ-------GSEDCLYLNVYT----RELHPHRPLPVLVWI 133
            .|:..|.......|.:|:    :|:::       .||||||||:||    ||   ...|||:|||
  Rat    84 GVRDGTSQPDMCLQTDIMKEDFIKEMKLTMHPTPMSEDCLYLNIYTPAHARE---GSNLPVMVWI 145

  Fly   134 YGGGFQMGEASRDLYSPDYIMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWV 198
            :|||..:|.||.::.| .....|.:|:|.|.||||.|||.|..||.  ..||.|..|||.||.||
  Rat   146 HGGGLVLGSASMNVAS-TLAATEEIVIVAIQYRLGILGFFSTGDEH--ARGNWGYLDQVAALCWV 207

  Fly   199 KRNCQFFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYR 263
            ::|..:|||:...:|:||.||||.|....:::..:|||||..|:.||.||.|
  Rat   208 QQNIAYFGGNHGKVTIFGVSAGGTSVSSHVVSPMSKGLFHGAIMQSGVALLP------------- 259

  Fly   264 LAQATGYTGDANDRDIFAHLKKCKASS--------MLKVAEDIITMEERHQRLTMFSFGPTIEPY 320
              .....|.:...:.: |:|..|:||.        ..|..::|:.:.:..:.:          |.
  Rat   260 --DLISDTSEVVYKTV-ANLSGCEASDSEALIRCLRAKSKQEILAINQVFKMI----------PG 311

  Fly   321 LTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFE---GLLMF---------------PEVNKWPEL 367
            :.....:||.|.|::.....:.:|.:||.|:.|   |:.||               |.|.|....
  Rat   312 VVDGKFLPKHPQELLASGDFHPVPSIIGVNTDECGLGVPMFMGLDHIIKKITRDTLPTVLKSTAA 376

  Fly   368 LCQL-GDCENLAPQDAHVDEQQRKAFGKKVRELYFGDRTPGRKTILE-YSDLF-SYKYFWHGIHR 429
            ...| .:|.:|                  :.|.|.|| |...:|:.| :.::. .:.:....:..
  Rat   377 QMMLPPECIDL------------------IMEEYMGD-TEDPETLQEQFKEMLGDFMFVIPALEV 422

  Fly   430 TLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVRGT----CHADDLSYLF---------- 480
            ....|:.    ||.:.|.|.      ::...|   ::||.:    .|.||:.::|
  Rat   423 AHFQRSQ----APVYFYEFQ------HLPSFI---KQVRPSHVKADHGDDILFVFSSYFWGMNFD 474

  Fly   481 YNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNI------PMVCQDEKEQPRGAWLPISKDDK 539
            .....:.||||..::         ..:||.:|:||.      |::  |..||    :|.::....
  Rat   475 ITEEEELLKRRVMKY---------WANFARNGNPNSEDLPYWPVL--DHNEQ----YLQLNTQPA 524

  Fly   540 VFQCLNISHDVHVIDLPEAEKLRLW 564
            |.:.|            :|.:|:.|
  Rat   525 VGRAL------------KARRLQFW 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	34..564	CDD:395084	166/597 (28%)
Ces2i	XP_008758816.2	COesterase	30..537	CDD:395084	166/600 (28%)