Protein Alignment alpha-Est8 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 637
• Identity: 170/637 - (26%)
• Similarity: 261/637 - (40%)
• Gaps: 164/637 - (25%)

  Fly    27 LRSNDKVIADTV---YGKVKGVKW---QSIYG--NNYYSFEGIPFAKPPVGELRFKAPVEPEHWS 83
            ||::.:..|.||   :||::|.:.   ..|.|  :.|.   |:|:|.||:||.||..|..|..||
Mouse    30 LRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYL---GVPYAAPPIGEKRFLPPEPPPSWS 91

  Fly    84 DVKRCTHV---------RAKP---------CQVNIVLKQVQ-GSEDCLYLNVYT----------- 118
            .::..||.         .|.|         ..::||...:| .:|||||||||.
Mouse    92 GIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQ 156

  Fly   119 ------------RELHPHRPLPVLVWIYGGGFQMGEASRDLYSPDYIMME--------HVVLVVI 163
                        .::......||:|:|:||.:..|..:         |::        :|:::.:
Mouse   157 GEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGN---------MIDGSVLASYGNVIVITL 212

  Fly   164 SYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMM 228
            :||:|.|||||..|:.  ..||.||.||:.|||||..|..||||||..|||||...|.:....:.
Mouse   213 NYRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT 275

  Fly   229 LTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDIFAHLKKCKASSMLK 293
            |:..::|||.:.||.|||||:.||.....:.:...||...|    .|..|....:...:..|..:
Mouse   276 LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVG----CNVLDTVDMVDCLRQKSAKE 336

  Fly   294 VAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGLLMF 358
            :.|..|.....|     .:|||.|:     ..|||..|..:|......:..:::|.|..|||...
Mouse   337 LVEQDIQPARYH-----VAFGPVID-----GDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFV 391

  Fly   359 PEVNKWPELLCQLGDCENLAPQDA------------HVDE-----QQRKAFGKKVRELY--FGDR 404
            ..|               :.|:|.            .||.     :.:....:.::.:|  :.||
Mouse   392 EGV---------------VDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADR 441

  Fly   405 ---TPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPL-APTFLYRFDFDSKHFNIMRIITCGR 465
               ...|||::.   ||: .:.|  :..::::...||.. :||:.|.|    .|.       |..
Mouse   442 DNPETRRKTLVA---LFT-DHQW--VEPSVVTADLHARYGSPTYFYAF----YHH-------CQS 489

  Fly   466 KVR----GTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVV-----HFAISGDPNIPMVCQ 521
            .::    ...|.|::.|:|..............|.....::|.||     :||.:||||.| |.|
Mouse   490 LMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKP-VPQ 553

  Fly   522 DEK---------EQPRGAWLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLW 564
            |.|         |:.  ||...:..|:::  |:|.....|.|...|.|:..|
Mouse   554 DTKFIHTKANRFEEV--AWSKYNPRDQLY--LHIGLKPRVRDHYRATKVAFW 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	167/633 (26%)
		Aes	<116..>221	CDD:223730	43/135 (32%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	166/626 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		0/20 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740