Protein Alignment alpha-Est8 and Ces2b

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 592
• Identity: 165/592 - (27%)
• Similarity: 250/592 - (42%)
• Gaps: 152/592 - (25%)

  Fly    34 IADTVYGKVKG----VKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAK 94
            |.:|..|:|:|    ||....   ..::|.||||||||||.|||..|..||.||.|:..|   |.
Mouse    35 IRNTHTGQVRGSLVHVKDTKA---GVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGT---AH 93

  Fly    95 PC----------QVNIVLKQVQGSEDCLYLNVYTRELHPHR--PLPVLVWIYGGGFQMGEASRDL 147
            |.          ::.:.|..|..||||||||:|| ..|.|.  .|||:|||:|||...|.||  :
Mouse    94 PAMCLQNLGVMKEIKLKLPPVSTSEDCLYLNIYT-PAHAHEGSNLPVMVWIHGGGLVAGMAS--M 155

  Fly   148 YSPDYI-MMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDN 211
            |....: .:|.:|:|.|.||||.|||.|..|:.  ..||.|..|||.||||:::|...|||.||.
Mouse   156 YDGSLLAAIEDLVVVTIQYRLGVLGFFSTGDQH--ARGNWGFLDQVAALRWIQQNIAHFGGKPDR 218

  Fly   212 ITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDAND 276
            :|:|||||||.|....:::..:|||||..|:.||.||.|:..|.|.......:|:.:|.  :|.|
Mouse   219 VTIFGESAGGTSVSSHVVSPMSKGLFHGAIMESGVALLPYLITDTSEMVSTTVAKLSGC--EAMD 281

  Fly   277 RDIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMM------ 335
            .:......:.|:.:.:.....::.|                .|.:......|:.|.|::
Mouse   282 SEALVRCLRGKSEAEILAINKLVQM----------------IPAVVDGEFFPRHPKELLASEDFH 330

  Fly   336 ---------RDCWGNSIPMVIGG-----------------NSFEGLLMFPEVNKWPELLCQLGDC 374
                     .|.:|.:||:|:|.                 |:...|::.||             |
Mouse   331 PVPSIIGVNNDEFGWTIPVVMGSAQTIKEITRENLQAVLKNTTAQLMLPPE-------------C 382

  Fly   375 ENLAPQDAHVDEQQRKAFGKKVRELYFGDRTPGRKTILEYSDLF-SYKYFWHGIHRTLLSRAHHA 438
            .:|                  :.|.|.||....:...::::::. .:.:....:......|:|
Mouse   383 SDL------------------LMEEYMGDTEDAQTLQIQFTEMMEDFMFVIPALQVAYFQRSH-- 427

  Fly   439 PLAPTFLYRFDFDSKHFNIMRIITCGRKVRGT----CHADDLSYLF-YNAAAKKLKRRTAEFKTI 498
              |..:.|.|...         |...:.||.|    .|||::.::| |.....||.....|....
Mouse   428 --ASVYFYEFQHQ---------IASLKDVRPTHVKADHADEIPFVFGYFFWDMKLDFTEGEKLLS 481

  Fly   499 KRLVSMVVHFAISGDPNI------PMVCQDEKEQPRGAWLPISKDDKVFQCLNISHDVHVIDLPE 557
            :|::....:||..|:||.      |::..||:      :|.:.....|.:.|            :
Mouse   482 RRMMKYWANFARHGNPNSEGLPYWPVMDHDEQ------YLQLDTQPAVGRAL------------K 528

  Fly   558 AEKLRLW 564
            :.:|:.|
Mouse   529 SRRLQFW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	164/590 (28%)
		Aes	<116..>221	CDD:223730	52/107 (49%)
Ces2b	NP_937814.1	COesterase	34..535	CDD:365897	164/590 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832697
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740