Protein Alignment alpha-Est8 and cest-31

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 152/533 - (28%)
• Similarity: 244/533 - (45%)
• Gaps: 106/533 - (19%)

  Fly    34 IADTVYGKVKGVKWQSIYGN-NYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHV--RAKP 95
            :.::..|.|:|..::  :|| ..:.:.|||:|:||:|.||||.||..:.|::.:.||..  |..|
 Worm    16 VLNSTCGPVQGNLYR--HGNEEVHGYLGIPYAQPPIGILRFKKPVSADVWTETRDCTKYGPRCPP 78

  Fly    96 CQV---NIVL--KQVQGSEDCLYLNVYTR--ELHPHRPLPVLVWIYGGGFQMGEASRDLYSPDY- 152
            ..:   |:.|  ..:....:||.|||:..  |:......||:::|:||||:: .||:|..  ||
 Worm    79 SGMLYENLQLPNTDIPDEANCLSLNVFCPQWEIKQSAKHPVMIFIHGGGFEL-SASKDYC--DYS 140

  Fly   153 ----IMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNIT 213
                :.::.|::|.::||:||||||:..|:  ...||.||.|..:||:||..:...|||||.|:|
 Worm   141 LSGTLPLKDVIVVTVNYRVGALGFLTTGDD--SCRGNFGLWDLTLALKWVSTHISSFGGDPKNVT 203

  Fly   214 VFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWA----QTPTHINWPYRLAQATGYTGDA 274
            :||:|||......:.|:..::.||||.|||||||..|:|    :....:...|..::....:|.|
 Worm   204 LFGQSAGAVCADLLNLSPYSRDLFHKLIIMSGSAHVPFAIRTEENQALVCMEYARSRGFSGSGSA 268

  Fly   275 NDRDIFAHL--KKCKASSMLK--VAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMM 335
            ...:.|.:|  :|....:.||  |:.|:             ||.|.::....|      .|||.:
 Worm   269 ELLEFFENLPIEKLLEKTGLKHTVSIDL-------------SFAPNLDGDFFP------KPLEEL 314

  Fly   336 RDCWGNSIPMVIGGNSFEGLL-MFPEVNKWPELLCQLGD---CENLAPQDAHVDEQQRKAFGKKV 396
            |. .....|:::|....|||: .|.:           ||   ||              :.|.::|
 Worm   315 RR-ETRKKPVIVGMMEDEGLITAFAD-----------GDFTTCE--------------ENFKRRV 353

  Fly   397 RELYFGDRTPG----RKTIL----EYSDLFSYK----YFWHGIHRT-------LLSRAHHAPLAP 442
            ...|.||....    :|.|:    .|.|....:    |..|.::..       .|:||.:.
 Worm   354 ESEYRGDVVENPENVQKNIMNFYTNYCDESEERKLVDYIGHSVYNAGVLLSAESLARAGNC---- 414

  Fly   443 TFLYRFDF-DSKHFNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVV 506
            .:.|.||| :...|..:..|.   ..:|..|..:|.|:.......|......:.|.::.:.:|..
 Worm   415 VYFYVFDFWNPDGFGPVGSIV---PFKGAAHCSELRYIIGEGVYSKFDANEKDLKMMEYMTTMFT 476

  Fly   507 HFAISGDPNIPMV 519
            :||..|:||||.|
 Worm   477 NFAKYGNPNIPGV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	152/533 (29%)
		Aes	<116..>221	CDD:223730	45/111 (41%)
cest-31	NP_504692.3	COesterase	16..522	CDD:278561	152/533 (29%)
		Aes	<112..>211	CDD:223730	43/103 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810