Protein Alignment alpha-Est8 and cest-7

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001257187.1
• Gene: cest-7 / 182819
• WormBaseID: WBGene00007693
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 137/540 - (25%)
• Similarity: 227/540 - (42%)
• Gaps: 100/540 - (18%)

  Fly    13 IALNYVKFKTNQQRLRSNDKVIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPV 77
            :||:...||            :.:|.||||:|:...|...|:.|.|:||||||||:|.|||..|.
 Worm    30 LALSVKSFK------------VLNTNYGKVRGITDFSDKRNHKYIFKGIPFAKPPLGLLRFALPE 82

  Fly    78 EPEHWSDVKRCTHVRAKPCQVNIVLKQVQG---SEDCLYLNVYTRELHPHRPLPVLVWIYGGGFQ 139
            ||..|:.|...:...| .|..|..|...|.   ||||||:|::|.|.......||||:.:||.|.
 Worm    83 EPNTWNGVLDGSKYSA-ACLSNSSLASAQQENISEDCLYINIFTSEYCLAHKCPVLVYYHGGSFN 146

  Fly   140 MGEASRDLYSPDYIMMEH-----VVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVK 199
            :..|:   ..||..::|.     :|..:.:||||..|...|.::.: ||.|..:.|.:.:|.:|.
 Worm   147 LDSAT---MFPDKFILERYVDSGIVFAIPAYRLGVFGQFYLGEQGI-VPANLLIHDCIRSLNFVH 207

  Fly   200 RNCQFFGGDPDNITVFGESAGGASTHYMMLTDQ---AKGLFHKTIIMSGSALAPWAQTPTHINWP 261
            .|...|||||:.:|:.|.|:||...:.|..::|   .|.||.:.|::  |::..:......|...
 Worm   208 DNIASFGGDPNYVTLMGHSSGGQLVNAMGFSNQIDPEKKLFQQFIVL--SSIGMYGFEDLQIGNS 270

  Fly   262 YRLAQATGYTGDANDRDIFAHLKKCKASSMLK---VAEDI-----------ITMEERHQRLTMFS 312
            |.:|:....|.: |.::|...::...|..:|:   |.:|:           ..:.:..|:|:.|.
 Worm   271 YEIARRHNCTSE-NSQEIVDCMRNIDALQLLQTQTVMDDVDLLFFKAIIRAPPLMDVKQKLSEFK 334

  Fly   313 FGPTIEPYLTPHCVI-------------------------PKSPLEMMRDCWGNSIPMVIGGNSF 352
            ...|....|   |.:                         |...:.:.|:.:.|..|..:..:|
 Worm   335 ENVTARNML---CGVTDNEFTIFKYPDGYYISATFLDFENPVDTVNVYRNKFTNITPTFVNSDS- 395

  Fly   353 EGLLMFPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFGKKVREL-YF-G-DRTPGRKTILEY 414
              ..:|.....:.|.|...|.       :.::.|.::|.|...|.:: || | .|.....|.::.
 Worm   396 --SAVFVSAATYSEALTNAGG-------NVYLFESRQKPFSMHVTDMQYFIGIHREKNHTTDMDI 451

  Fly   415 SDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIIT---CGRKVRGTCHADDL 476
            .|.|..|        .|::.......:|.: .::|....:|..|.|.|   ...|:....|.:.:
 Worm   452 LDSFYSK--------LLVNFTKFGSPSPNW-EKYDPSKMNFMAMEIDTEQGIEPKMENGFHEELV 507

  Fly   477 SYLFYNAAAKKLKRRTAEFK 496
            ::...|  ..::.|...|.|
 Worm   508 NFWLIN--MMQIDRNIIEMK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	133/524 (25%)
		Aes	<116..>221	CDD:223730	35/109 (32%)
cest-7	NP_001257187.1	Abhydrolase	34..510	CDD:304388	131/517 (25%)
		Aes	<135..>236	CDD:223730	35/104 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157157
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840