Protein Alignment alpha-Est8 and cest-30

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 155/603 - (25%)
• Similarity: 247/603 - (40%)
• Gaps: 138/603 - (22%)

  Fly    23 NQQRLRSNDKVIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKR 87
            |.|.|.:....|...:|....|.|...       .:.||||||.|||.|:||.||..|.|::.:.
 Worm    30 NSQILNAPCGPIRGNIYKHKNGTKIVD-------GYLGIPFAKAPVGALKFKKPVAAEKWTEPRD 87

  Fly    88 CTHVRAKPCQVN----IVLKQVQ--GSEDCLYLNVYTRELHPH-------RPLPVLVWIYGGGFQ 139
            |........|..    :..|...  ..|:||.|||:.    |.       :.|||||:|||||::
 Worm    88 CYEYGPGCPQTGRFAALTAKSTAAFAEENCLTLNVFA----PRWKLAEFPKGLPVLVYIYGGGYE 148

  Fly   140 MGEASRDLYSPDY-----IMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVK 199
            :|..|   |..||     :.::.|::|.::||||.||||::||...:  ||.||.||.:||:||:
 Worm   149 IGFTS---YMDDYSLTGTLPLKDVIVVTMNYRLGPLGFLTIADGIAN--GNYGLWDQTLALQWVQ 208

  Fly   200 RNCQFFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTP--THINWPY 262
            .|...|||:|:::|:.|.|||..||.::.|:..:..||.::|.|||:|...:|..|  ..:....
 Worm   209 DNIASFGGNPESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTAFCNFAIRPKDVEVGVCK 273

  Fly   263 RLAQATGYTGDANDRDIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIE---PYLTPH 324
            ..||..|||| .:.:.:|........|...:||                .|..|..   |:: |:
 Worm   274 EFAQFQGYTG-TDSQSLFDWYMAQNVSKFKEVA----------------GFQSTAAGAVPFI-PN 320

  Fly   325 C---VIPKSPLEMMRD-----------CWGNSIPMVI-------GGNSFEGLLMFPEVNKWPELL 368
            .   ..|| |.:::|.           ....|:.|:|       ..|:|||.:.
 Worm   321 FDGDFFPK-PFDILRREAPKKDALITVVTMESVGMIIFNPLFANAYNNFEGFIN----------- 373

  Fly   369 CQLGDCENLAPQ--DAHVDEQQRKAFGKKVRELYFGDRTPGRKTILEYSDLFSYKYFWHGIHRTL 431
                  |...|.  |.:.| .::|..|..::::...|:....:.:::|   .|...|..|....:
 Worm   374 ------ETYGPDVTDYYAD-VKKKLTGFYLKDVNASDKATVNRRVVDY---VSDSVFNSGTLDAV 428

  Fly   432 LSRAHHAPLAPTFLYRFDFDSKHFN--IMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAE 494
            .|...:.  ...:|..|::    ||  ...::...:..:...|:.|..|.|.:...........|
 Worm   429 KSYVKYG--NKVYLGSFNY----FNDATKDMVELMQPFKEASHSSDFKYYFGSGVMANFTPTDEE 487

  Fly   495 FKTIKRLVSMVVHFAISGDPNIPMVCQDEKEQPRGAWLP--ISKDDKVFQCLNISHDVHVIDLPE 557
            .:.:....:::.:|...||||        .:.....|.|  |.|.:..::          ||.|.
 Worm   488 MEVMDMSGTLMANFVKYGDPN--------GKSGTKPWKPYTILKPNMYYK----------IDYPT 534

  Fly   558 AE--------KLRLWDCI 567
            .|        :||::|.|
 Worm   535 CEMSDNFQNGRLRIYDDI 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	150/592 (25%)
		Aes	<116..>221	CDD:223730	48/116 (41%)
cest-30	NP_504407.1	COesterase	31..539	CDD:278561	150/587 (26%)
		Aes	<122..>230	CDD:223730	48/116 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157266
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740