Protein Alignment alpha-Est8 and cest-9.1

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 112/459 - (24%)
• Similarity: 188/459 - (40%)
• Gaps: 93/459 - (20%)

  Fly    32 KVIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPC 96
            ||| .|.|||::|:...|...|:.|.|:.:||||||||.|||..|..||.||.:...:.. :..|
 Worm    19 KVI-QTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQNPESWSGILDASKY-SPAC 81

  Fly    97 QVN---IVLKQVQGSEDCLYLNVYTRELHPHRPLPVLVWIYGGGFQMGEA--SRDLYSPDYIMME 156
            ..|   ....|...||||||:|::|.|...:...||:|:.:||.:.:..|  ..|.:..|....|
 Worm    82 MSNSSSTSTPQKHYSEDCLYINIFTSEKCLNSKCPVIVYFHGGAYNLDSAIMFNDTFILDRYAAE 146

  Fly   157 HVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGG 221
            .||.|:.:.|||..|.|.....:| :..|..|.|.|.||.:|.....:||||...:|..|.|:||
 Worm   147 DVVFVIPAVRLGVFGQLYFGPSDL-LSENLFLYDAVQALSFVHSEINYFGGDSKRVTAMGHSSGG 210

  Fly   222 A---STHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATG-YTGDANDR----- 277
            .   :..:..|.|....||.:.|::|.:.:..:....  ::..:.:.:..| |.|..:||
 Worm   211 TIVDALGFSKLIDPGVKLFQQMIVLSATGMFGFYDMV--VDNSFAIVEKFGCYNGTKDDRPNANI 273

  Fly   278 -DIFAHLKKCKASSMLKVAEDIITMEERHQRLTM-----------------------FSFGPT-- 316
             ::...:::.....||.:...:..:::|..|..:                       ..:|.|
 Worm   274 AEMLDCMRQIDGREMLLMQRHMEEVDDRDFRSVLRGAPFLESNGKIADLKKSPPSRNLLYGTTEH 338

  Fly   317 -------IEPYLTPHCVIPKSPLEMMR----DCWGNSIPMVIGGNSFEGLLMFPEVNKWPELLCQ 370
                   :.||::...:...:|:.:.|    ....|...|:.|    :...:|...:.:...:..
 Worm   339 EFRNVDHMNPYISGIFLDFDNPVAVARYYDEQLMANLETMING----DAAAIFICASTFSTAMAN 399

  Fly   371 LGDCENLAPQDAHVDEQQRKAFGKKVRELYFGDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSRA 435
            .|       .|.::.|.::|.:...|.::                     :|| .||||.:
 Worm   400 TG-------ADVYLFETRQKPYSFHVSDM---------------------QYF-VGIHREI---- 431

  Fly   436 HHAP 439
            :|.|
 Worm   432 YHRP 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	112/459 (24%)
		Aes	<116..>221	CDD:223730	34/106 (32%)
cest-9.1	NP_001359584.1	Abhydrolase	19..498	CDD:389770	112/459 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157191
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740