Protein Alignment alpha-Est8 and cest-2.1

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 134/555 - (24%)
• Similarity: 228/555 - (41%)
• Gaps: 115/555 - (20%)

  Fly    37 TVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQVNIV 101
            |:.||:....:..:..:....|.||||.:||.|.|||:.|..|..|..:......  ||..::..
 Worm    27 TIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEY--KPACMSDA 89

  Fly   102 LKQVQG------SEDCLYLNVYTRELHPHRP-LPVLVWIYGGGFQMGEASRDLYSPDYIMM---- 155
            .|..:.      ||||||.||:|.:....|. ..|::.::||......||  .::|:.::.
 Worm    90 KKTYKNGVGGPISEDCLYANVFTNQYCMKRKNCSVMIVVHGGRILTESAS--AFNPEILVNNFVG 152

  Fly   156 --EHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGES 218
              .::|:|..:||||..||..|..|:.|  .|.|:.|.:.|::|.::....|||:.|.:|:.|.|
 Worm   153 QGRNIVVVTFNYRLGTFGFGVLNGEKGD--SNVGMFDMLEAVKWTRKEVHNFGGNKDKLTMVGHS 215

  Fly   219 AGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDR----DI 279
            |||:.......:..:||:.::.||||| ||....          :||...|.|..|...    ::
 Worm   216 AGGSLVGAFTSSPLSKGMLNQQIIMSG-ALYQMG----------KLANFKGMTAMAQKAGCLPEV 269

  Fly   280 FAHLKKC-----KASSMLK--VAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRD 337
            |...|..     |..|.|:  .|::::..:....:.|.:...   .|::....::..|. |::..
 Worm   270 FGFRKLSQVRIDKTYSCLRNISAQEVLDAQLWVLQNTTYYIS---VPHIDGEFLLNYSD-EILAS 330

  Fly   338 CWGNSIPMVIGGNSFEGLLMFP-------EVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFGKK 395
            ...:.|..:||..:.|  |..|       ..:|..|||..|  ||::. .:.:.:.::   |.:|
 Worm   331 GTIHPINSMIGTTTAE--LRDPIYINDLKNADKKEELLKNL--CEHIG-YELYTEPEE---FSRK 387

  Fly   396 VRELY-FGDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMR 459
            .::.| .||........:|:.| .|.|          ::.||.:.....|:|.:|:
 Worm   388 CQKFYGNGDDAQFLADDMEFYD-GSIK----------VANAHASKNTKVFMYSYDY--------- 432

  Fly   460 IITCGRKVRGTC-----------HADDLSYLFYNAAAKKLKRRTAEFKTIKRLVS-MVVHFAISG 512
                  |..|..           |::||.|:|..:..    ..|.:...|:::.| |...|...|
 Worm   433 ------KDAGPAFKKYAQAPPPHHSEDLIYVFGTSRG----NFTEKDYVIEQIYSGMFADFVNFG 487

  Fly   513 DPNIPMVCQDEKEQPRGAWLPISKD------DKVF 541
            :|:      ..|||....:.|..::      ||.|
 Worm   488 NPS------PSKEQKWKEYSPEKREYFLIDFDKNF 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	134/555 (24%)
		Aes	<116..>221	CDD:223730	33/111 (30%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	134/555 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740