Protein Alignment alpha-Est8 and cest-35.1

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 161/585 - (27%)
• Similarity: 259/585 - (44%)
• Gaps: 116/585 - (19%)

  Fly    15 LNYVKFKTNQQRLRSNDKVIADTVYGKVKGVKWQSIYGNN---YYSFEGIPFAKPPVGELRFKAP 76
            |:::|.:.|.:.|.::        .|.::|    :||.::   ...:.||||||.|:||||||..
 Worm     5 LSHLKPEHNTEVLNAS--------CGPIRG----NIYEHDDKIVDGYLGIPFAKAPIGELRFKKS 57

  Fly    77 VEPEHWSDVKRCTHVRAKPCQVN-----IVLKQVQ-----GSEDCLYLNVYT---RELHPHRPLP 128
            ||.|.|::...| :.....|..:     :::.|..     ..::||.|||:.   :.......||
 Worm    58 VEAEKWTEPLDC-YKYGPGCPQSGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPNGLP 121

  Fly   129 VLVWIYGGGFQMGEASR-DLYS-PDYIMMEHVVLVVISYRLGALGFLSLADEELDVP-GNAGLKD 190
            |:|:.|||||::|.:|. |.|| ...:.::.|:||..:||:|.|||.:..|   ||. ||.||.|
 Worm   122 VIVYFYGGGFEVGFSSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGD---DVSRGNWGLWD 183

  Fly   191 QVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTP 255
            |.:||:||:::.:.|||||.|:|:.|.||||||..::.|:..|...|||.|.|||:|..|:....
 Worm   184 QALALQWVQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGAATCPFGIRS 248

  Fly   256 THINWPY--RLAQATGYTGDANDRDIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIE 318
            ..:....  ..|:..||.|  ||.:...|..:.:.:.:...||..     ::....||||.|..:
 Worm   249 KDVEGLIFREFAKHHGYAG--NDSESLLHWYQSQDAEIFLKAEGF-----KYPASGMFSFVPNYD 306

  Fly   319 PYLTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGL---LMFPEVNKWPELLCQLGDCENLAPQ 380
            ....|      .|.:.:|. ....:..::....:|||   ..:|......|:|...     |.|:
 Worm   307 GDFFP------KPFDELRK-EAPKLDAIVSVAEYEGLGFEEFYPGQKSPQEVLTAA-----LGPE 359

  Fly   381 DAHVDEQQRKAFGKKVRELYF-------GDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHA 438
            ..    :.|:...||..|.|.       |::. |:|.:    ::|...||..|:..|:.|.|.:.
 Worm   360 VV----RNREEVVKKAVEAYLENIEDKSGEKI-GKKLV----EIFGDYYFSVGVFDTVRSLAKYG 415

  Fly   439 PLAPTFLYRFDFDSKHFNIMRIITCG--RKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRL 501
                ..:|...|:  :||....|..|  |......|..|:.|:..:...:..|.   :.|.:..:
 Worm   416 ----NNVYLSSFN--YFNPETPIMFGENRPFNAASHGCDIRYILGDGIGEFSKE---DRKVMDMM 471

  Fly   502 VSMVVHFAISGDPN-----IPMVCQDEKEQPRGAWLPISKDD--KVFQCLNISHDVHVIDLPEAE 559
            .:.:.:||..|:||     ||             |...|.|:  :.|:          ||.|:.|
 Worm   472 GTYLTNFAKYGNPNGKGVSIP-------------WEKYSLDNPGRYFK----------IDYPKCE 513

  Fly   560  559
             Worm   514  513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	157/571 (27%)
		Aes	<116..>221	CDD:223730	47/110 (43%)
cest-35.1	NP_504400.1	COesterase	14..516	CDD:278561	158/576 (27%)
		Aes	<106..>214	CDD:223730	47/110 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740