Protein Alignment alpha-Est8 and ges-1

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 175/579 - (30%)
• Similarity: 262/579 - (45%)
• Gaps: 96/579 - (16%)

  Fly    34 IADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQV 98
            |.:|.||||:|::::..     ..|..||||||||.:|||:.||.|:.|.||...|..| ..|..
 Worm    19 IVETNYGKVEGIEYEGA-----EVFLAIPFAKPPVDDLRFEKPVAPDPWEDVYPATQYR-NDCTP 77

  Fly    99 NIVLKQVQGS---EDCLYLNVYTRELHPHR--PLPVLVWIYGGGFQMGEASR---DLYSPDYIMM 155
            :..|.....|   ||||.||:    :.|.:  .||||.||:|||:::|.||:   :.::..| ..
 Worm    78 HYRLVAQFSSYSGEDCLTLNI----IKPKKAEKLPVLFWIHGGGYEIGSASQHGYEFFAKRY-AS 137

  Fly   156 EHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAG 220
            :.|::..:.||||.:||.|  :...||.||.||.||..||.:||.|.:.|||||:.||::|.|||
 Worm   138 QGVIVATVQYRLGFMGFFS--EGTSDVQGNWGLFDQAAALEFVKSNIENFGGDPNQITIWGYSAG 200

  Fly   221 GASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATG--YTGDANDRDIFAHL 283
            .||...:.::...:..:.|.||||.|:...||..|..:....:||:..|  :.|          .
 Worm   201 AASVSQLTMSPYTRDSYSKAIIMSASSFVGWATGPNVVETSKQLAEILGCPWPG----------A 255

  Fly   284 KKC-KASSMLKVAEDIITMEERHQRLTMFSFGPTIE-PYLT--PHCVIPKSPLEMMRDCWGNSIP 344
            |:| |..|:.::.:.|.........:.:..:.|.|: .::|  |..:|.:||::          |
 Worm   256 KECMKKKSLHEIFDAIEVQGWTTGTIDILRWSPVIDGDFMTKNPEELIKESPVK----------P 310

  Fly   345 MVIGGNSFEGLLMFPEVNKWPELLCQLGDCENLAPQD-AHVDE------------------QQRK 390
            .:||.::.|| ..|..:| ...::...|    |:|:| ..|||                  :.|:
 Worm   311 TLIGMSNKEG-SYFAALN-MGRVIADFG----LSPEDMPKVDEEFISEIIGRKLLYNNRYGENRE 369

  Fly   391 AFGKKVRELYFGDRTPGRKTIL------EYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFD 449
            .....:.:.|.....|.....|      .||:|.|...|...|.|.:.||....  .|.:.||.|
 Worm   370 KVWNDILDFYVKQGKPAEVKDLNGFYVDRYSELLSDITFNVPILREITSRVERK--TPVWTYRMD 432

  Fly   450 FDSKHFNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKR-LVSMVVHFAISGD 513
            ...|:.....|   ..:.||:.||::..|||......|:..:......|:. |:.||:.||.:|.
 Worm   433 HYDKNIWKKHI---PEQARGSPHANEYHYLFDMPVMAKIDMKKEPDSWIQNDLIDMVISFAKTGV 494

  Fly   514 PNIPMVCQDEKEQPRGAWLPISKDDKVFQCLNISHD-VHVIDLPEAEKLRLWDCIYDRE 571
            |.|..|          .|.|:|..|.| ..|||..| |.:......|.|..|:.:..||
 Worm   495 PQIEDV----------EWRPVSDPDDV-NFLNIRSDGVSIEHGLFQEPLAFWNELRQRE 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	172/570 (30%)
		Aes	<116..>221	CDD:223730	45/109 (41%)
ges-1	NP_503411.1	COesterase	18..535	CDD:278561	172/570 (30%)
		Aes	<100..>211	CDD:223730	48/113 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222591at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17029
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850