Protein Alignment alpha-Est8 and cest-5.1

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 144/601 - (23%)
• Similarity: 225/601 - (37%)
• Gaps: 154/601 - (25%)

  Fly    27 LRSNDKVIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHV 91
            :.:.|.:|..|.:|.::|.:.     .:|:.|:.|||||||||.|||:.|.....|..::.....
 Worm    13 INAADSLIIHTSFGHLEGAEI-----GDYHLFKKIPFAKPPVGNLRFQKPEAAGKWDGIRSAIEY 72

  Fly    92 RAKPCQVN---IVLKQVQGSEDCLYLNVYT-RELHPHRPLPVLVWIYGGGFQMGEA--SRDLYSP 150
             ...|..|   ....|....||||::|::| ::....|...:.|:|:|||.....|  ..|....
 Worm    73 -GPACMSNSSKTKSPQKWVDEDCLHVNIFTSKKCLKSRNCAIAVYIHGGGLTYDSAVMFNDTVLL 136

  Fly   151 DYIMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVF 215
            |..:...|:||:..:|||.....::.::.: .|.|..|.|..:||.:||.....|||:...||:|
 Worm   137 DTFVKRDVILVIPGFRLGIFSHFTVHNQNV-APNNLALYDITLALEFVKSEIHSFGGNSQKITLF 200

  Fly   216 GESAGGASTHYMMLTDQAK---GLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDR 277
            |.|.||.....|..:.:..   .||.:.|:|||...  :.:...||....|
 Worm   201 GHSYGGGLASMMTFSSEINRDLSLFQQAIVMSGGFY--FEELKDHIEGTKR-------------- 249

  Fly   278 DIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNS 342
              |.....|  |..||:..   .||...|.:.|..            |:...|.:|::|
 Worm   250 --FVEYANC--SVPLKLER---KMERSQQEMYMMK------------CLQKLSGMELLR------ 289

  Fly   343 IPMVI---GGNSFEGLL----MFPEVNKW-----PELLCQLGDCENLAPQDAHVDEQQRKA-FGK 394
            |..::   |...|.|::    :||:|.|:     |:.:..|..|.||     ..|.:..|. |||
 Worm   290 IQRLLEDKGYPDFGGVILREPLFPDVKKFELLKSPKNIPMLTGCTNL-----EFDHESIKVPFGK 349

  Fly   395 KVRELYFGDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHA--------PL----------- 440
            .:.              .|..|....|| .:.:...:.:|.:|.        ||
 Worm   350 YLE--------------FENPDECDEKY-RNDVESGVENRGNHTDKTQGIILPLKLQINNLLENN 399

  Fly   441 APTFLYRFDFDSKHFNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMV 505
            ...:||.:.: .||         ||      |.|||||:....|.:|.:......:..|   .||
 Worm   400 VTAYLYEYTY-PKH---------GR------HTDDLSYIMGVHAFEKDENEVHLEQVYK---DMV 445

  Fly   506 VHFAISGDPNIPMVCQDEK--------------EQPR----------GAWLP--ISKDDKVFQCL 544
            ::|...|:|.:.....::.              |:||          ..||.  |..|.||.:..
 Worm   446 INFIKLGEPGMGFEKSEQNESTYFDIYWNETTGERPRMRKYFEKEVTDYWLKEMIEFDQKVTETK 510

  Fly   545 NISHDVHVIDLPEAEK 560
            .....:.:..:|..||
 Worm   511 KKLKQISLKTVPFIEK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	144/599 (24%)
		Aes	<116..>221	CDD:223730	32/107 (30%)
cest-5.1	NP_501022.3	Abhydrolase	19..495	CDD:389770	134/562 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156905
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740