Protein Alignment alpha-Est8 and cest-5.2

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 526
• Identity: 123/526 - (23%)
• Similarity: 201/526 - (38%)
• Gaps: 114/526 - (21%)

  Fly    34 IADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQV 98
            |..|..|:::|.:     ...|..|..|||||||:|.|||:.|...|.|:.|...|.. ...|..
 Worm    23 IIKTSLGRLEGKQ-----SGKYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEY-GPACMS 81

  Fly    99 NIVLKQVQG---SEDCLYLNVYTRE-LHPHRPLPVLVWIYGGG--FQMGEASRDLYSPDYIMMEH 157
            |....|...   .||||::|::|.: ....:...|:|:|:||.  |.......|.:..:..:.:.
 Worm    82 NSTWTQSPQKWVDEDCLHVNIFTSDKCLKSKDCAVVVYIHGGEIVFDSAVMFNDTFLLESFVKQD 146

  Fly   158 VVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGA 222
            |:||:.::|||.....::.|:.: .|.|..|.|.::|..:||.....||||...||:||.|.||.
 Worm   147 VILVIPAFRLGIFSHFTVHDQNI-APNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYGGT 210

  Fly   223 STHYMMLT---DQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDIFAHLK 284
            ....|..:   :|...||.:.|:||.:......:....     |..:...:.|.:...::...:.
 Worm   211 IASMMAFSSEINQDLSLFQRIIVMSANQYFDTLEEQIE-----RSDRVVKHAGCSVPTNLARKMN 270

  Fly   285 KC-KASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIG 348
            :. |...|:|..:.:..||       :.|...::|....|..              ||   :|:.
 Worm   271 RSQKEKYMMKCLQKLSGME-------LLSVQRSLEEAGYPDI--------------GN---LVLR 311

  Fly   349 GNSFEGLLMFPEVN-----KWPELLCQLGDCENLAPQDAHVDEQQRKAFGKKVRELYFGDRTPGR 408
            |.      :||:|.     :.|:::..|..|......    ||.:....||     :||...|
 Worm   312 GP------LFPDVTSLEMLESPKMIPMLAGCTKFESD----DEDETHFIGK-----HFGLENP-- 359

  Fly   409 KTILEYSDLFSYKYFWHGIHRTLLSRAHH-----APLAPT--------------FLYRFDFDSKH 454
               :|..:.:. |...:||    ..|.:|     |.:.||              :||.|.:....
 Worm   360 ---IECDEKYR-KDLENGI----FDRQNHSDKTQAIMVPTKLRVDQLRKHGVPAYLYEFTYPKHA 416

  Fly   455 FNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNIPMV 519
            |                |.|||.|:.   .....::...|....|...:|:::|...|:|.:...
 Worm   417 F----------------HTDDLYYIM---GIHPFEKDENEEHLEKVYRNMLINFIKFGEPGMGFE 462

  Fly   520 CQDEKE 525
            ..|..|
 Worm   463 MSDLNE 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	123/526 (23%)
		Aes	<116..>221	CDD:223730	31/107 (29%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	123/526 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156888
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740