Protein Alignment alpha-Est8 and ace-4

DIOPT Version :10

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 158/599 - (26%)
• Similarity: 232/599 - (38%)
• Gaps: 154/599 - (25%)

  Fly    33 VIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQ 97
            |:.:|..|.:||.:: ........:|.|:|||:|.|.:.||:.|.|.:.|..:...|    ||..
 Worm    27 VVLETKLGDIKGTEF-FFLSKKIRTFFGVPFAEPAVEDFRFRKPREKKQWRGLYDAT----KPAN 86

  Fly    98 VNIVLK---------------QVQGSEDCLYLNVYTRELHPHRP-----LPVLVWIYGGGFQMGE 142
            .....:               ..|.||||||||::.       |     |.|:||.:||||..|.
 Worm    87 ACFQTRDNYNTSFWGSEMWNANTQISEDCLYLNIWA-------PADAYNLTVMVWFFGGGFYSGS 144

  Fly   143 ASRDLYSPDYI-MMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFG 206
            .|..:|....: ..::|::|.|:||||..|||.|...  |.|||.||.||.:||.||::|...||
 Worm   145 PSLSIYDGKALTSTQNVIVVNINYRLGPFGFLYLGHP--DAPGNMGLLDQQLALHWVRQNIVSFG 207

  Fly   207 GDPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYT 271
            |:||.:.|||:|||.||....::...::|||...|:.|||....||     ||.|:|..|.:
 Worm   208 GNPDKVAVFGQSAGAASIVAHLIAPGSRGLFKNAILQSGSLENTWA-----INSPFRAKQKS--- 264

  Fly   272 GDANDRDIFAHLKKCKASS-------MLKVAEDIITMEERHQRLTMFSFGPTIEP-------YLT 322
                  :....|..|..::       :..|:.:.:::...:..||...|...|..       :|.
 Worm   265 ------EKLLELVGCNKTTVDTSMACLRLVSPEQLSLSTWNISLTYLEFPFVIVSRDKHFFGHLD 323

  Fly   323 PHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGLLMFPEVNKW--------------PELLCQLGD 373
            .|..:.:.  :..||     :.::||.|..||       |.|              |||
 Worm   324 AHAALREG--DFNRD-----VNLMIGMNKDEG-------NYWNIYQLPQFFDKADPPEL------ 368

  Fly   374 CENLAPQDAHVDEQ---QRKAFGKKVRELYFGDRTP--GRKT----------ILEYSDLFSYKYF 423
              |....|..:|..   |........:.:|......  ||||          :.:|  .||....
 Worm   369 --NRTEFDFLIDRTFSIQPDIIRSAAKYIYSDPNCTDHGRKTRFYAGQMNQIVGDY--FFSCDSL 429

  Fly   424 W-----HGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVRGTCHADDLSYLF--- 480
            |     ..|.|...|.....| ...|:|       ||..........|..|..|..::.|:|
 Worm   430 WLADQFRSIPRVKSSSPQRKP-GKVFVY-------HFTQSSSANPWPKWTGAMHGYEIEYVFGIP 486

  Fly   481 --YNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNIPMVCQDE-----KEQPRGAWL------ 532
              |   :|..|||...|.  ::::.....||.:|.|.:.::...|     .||....|:
 Worm   487 LSY---SKNYKRREQIFS--RKIMQFWASFAKNGTPKLRVLKNSEHWPEFNEQNHYRWMQLRSGS 546

  Fly   533 ---PISKDDKVFQC 543
               || |..|..:|
 Worm   547 NIRPI-KPKKQVEC 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	34..564	CDD:395084	157/598 (26%)
ace-4	NP_496962.1	COesterase	28..562	CDD:395084	157/598 (26%)