Protein Alignment alpha-Est8 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 657
• Identity: 172/657 - (26%)
• Similarity: 266/657 - (40%)
• Gaps: 184/657 - (28%)

  Fly    27 LRSNDKVIADTV---YGKVKGVKW---QSIYG--NNYYSFEGIPFAKPPVGELRFKAPVEPEHWS 83
            ||::.:..|.||   :||::|.:.   ..|.|  :.|.   |:|:|.||:||.||..|..|..||
  Rat    33 LRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYL---GVPYAAPPIGEKRFLPPEPPPSWS 94

  Fly    84 DVKRCTHV---------RAKP---------CQVNIVLKQVQ-GSEDCLYLNVY--TREL------ 121
            .::..||.         .|.|         ..::||...:| .:|||||||||  |.::
  Rat    95 GIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKE 159

  Fly   122 ---HPHRPL--------------------------------PVLVWIYGGGFQMGEASRDLYSPD 151
               .|::.:                                ||:|:|:||.:..|..:
  Rat   160 CARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGN------- 217

  Fly   152 YIMME--------HVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGD 208
              |::        :|:::.::||:|.|||||..|:.  ..||.||.||:.|||||..|..|||||
  Rat   218 --MIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWVSENIAFFGGD 278

  Fly   209 PDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGD 273
            |..|||||...|.:....:.|:..::|||.:.||.|||||:.||.....:.:...||...|
  Rat   279 PRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVG---- 339

  Fly   274 ANDRDIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDC 338
            .|..|....:...:..|..::.|..|.....|     .:|||.|:     ..|||..|..:|...
  Rat   340 CNVLDTVDMVDCLRQKSAKELVEQDIQPARYH-----VAFGPVID-----GDVIPDDPEILMEQG 394

  Fly   339 WGNSIPMVIGGNSFEGLLMFPEVNKWPELLCQLGDCENLAPQDA------------HVDE----- 386
            ...:..:::|.|..|||.....|               :.|:|.            .||.
  Rat   395 EFLNYDIMLGVNQGEGLKFVEGV---------------VDPEDGVSGTDFDYSVSNFVDNLYGYP 444

  Fly   387 QQRKAFGKKVRELY--FGDR---TPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPL-APTFL 445
            :.:....:.::.:|  :.||   ...|||::.   ||: .:.|  :..::::...||.. :||:.
  Rat   445 EGKDTLRETIKFMYTDWADRDNPETRRKTLVA---LFT-DHQW--VEPSVVTADLHARYGSPTYF 503

  Fly   446 YRFDFDSKHFNIMRIITCGRKVR----GTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVV 506
            |.|    .|.       |...::    ...|.|::.|:|..............|.....::|.||
  Rat   504 YAF----YHH-------CQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVV 557

  Fly   507 -----HFAISGDPNIPMVCQDEK---------EQPRGAWLPISKDDKVFQCLNISHDVHVIDLPE 557
                 :||.:||||.| |.||.|         |:.  ||...:..|:::  |:|.....|.|...
  Rat   558 MTYWTNFAKTGDPNKP-VPQDTKFIHTKANRFEEV--AWSKYNPRDQLY--LHIGLKPRVRDHYR 617

  Fly   558 AEKLRLW 564
            |.|:..|
  Rat   618 ATKVAFW 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	169/653 (26%)
		Aes	<116..>221	CDD:223730	45/155 (29%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	169/648 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		0/25 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336089
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740