Protein Alignment alpha-Est8 and Cel

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_034015.1
• Gene: Cel / 12613
• MGIID: 88374
• Length: 599
• Species: Mus musculus
• Alignment Length: 565
• Identity: 170/565 - (30%)
• Similarity: 248/565 - (43%)
• Gaps: 83/565 - (14%)

  Fly    40 GKVKGV--KWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQVNIVL 102
            |.|:||  |...:.|::...|:|||||....    .:.|.....|....:.|:.:.:..|..|..
Mouse    31 GFVEGVNKKLSLLGGDSVDIFKGIPFATAKT----LENPQRHPGWQGTLKATNFKKRCLQATITQ 91

  Fly   103 KQVQGSEDCLYLNVYT---RELHPHRPLPVLVWIYGGGFQMGEASRDLYSPDYI-------MMEH 157
            ....|.|||||||::.   |:...|. |||:||||||.|.||......:..:|:       ...:
Mouse    92 DNTYGQEDCLYLNIWVPQGRKQVSHN-LPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGN 155

  Fly   158 VVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGA 222
            |::|..:||:|.|||||..|..|  |||.||:||.||:.|||||...|||||||||:||||||.|
Mouse   156 VIVVTFNYRVGPLGFLSTGDANL--PGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAA 218

  Fly   223 STHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDIFAHLKKCK 287
            |.....|:...|||..:.|..||.||:|||.....:.|...:|:..|.  ...|....|...|..
Mouse   219 SVSLQTLSPYNKGLIRRAISQSGMALSPWAIQKNPLFWAKTIAKKVGC--PTEDTGKMAACLKIT 281

  Fly   288 ASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNS--IPMVIGGN 350
            ....|.:|..:...::.:..:...:|.|.|:...     ||..|:.:    :.|:  |..:.|.|
Mouse   282 DPRALTLAYKLPVKKQEYPVVHYLAFIPVIDGDF-----IPDDPINL----YNNTADIDYIAGIN 337

  Fly   351 SFEGLLM----FPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFGKKVRELYFGDRTPG---- 407
            :.:|.|.    .|.|:|..:.:.: .|...|.  ..|.     .|.|.|..:..|...|..
Mouse   338 NMDGHLFATIDVPAVDKTKQTVTE-EDFYRLV--SGHT-----VAKGLKGAQATFDIYTESWAQD 394

  Fly   408 ------RKTILEY-SDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGR 465
                  :||::.: :|:.    |.......|.....||..|.|:.|.|...|:    |.|..
Mouse   395 PSQENMKKTVVAFETDVL----FLIPTEIALAQHKAHAKSAKTYSYLFSHPSR----MPIYP--- 448

  Fly   466 KVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNI---PMVCQDEKEQP 527
            |..|..|||||.|:|....|..|..|..:....|.:::...:||.|||||:   |:...
Mouse   449 KWMGADHADDLQYVFGKPFATPLGYRPQDRAVSKAMIAYWTNFARSGDPNMGNSPVPTH------ 507

  Fly   528 RGAWLPISKDDKVFQCLNISHDVHVIDLPE--AEK-LRLWDCIYD 569
               |.|.:.::..:  |:|:..:....:.|  .|| |:.|...::
Mouse   508 ---WYPYTLENGNY--LDITKTITSASMKEHLREKFLKFWAVTFE 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	169/558 (30%)
		Aes	<116..>221	CDD:223730	55/114 (48%)
Cel	NP_034015.1	COesterase	26..542	CDD:278561	169/558 (30%)
		Aes	<117..>247	CDD:223730	65/132 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..599
		4 X 11 AA tandem repeats, O-glycosylated region	559..588

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740