Protein Alignment alpha-Est8 and clt

DIOPT Version :10

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Alignment Length: 561
• Identity: 186/561 - (33%)
• Similarity: 289/561 - (51%)
• Gaps: 40/561 - (7%)

  Fly    26 RLRSNDKVIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVK-RCT 89
            |..|:.||......|.:.|.:.:.:.|..|.||.|:|:|:||||||||::|...|.:...: .|:
  Fly    13 RFCSSMKVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCS 77

  Fly    90 HVRAKPCQVNIVLKQVQGSEDCLYLNVYTRELHPHR-PLPVLVWIYGGGFQMGEASRDLYSPDYI 153
            .......|.:....:|.||||||:||||..::...| ||||:|||:||||..|..:.|.:.|..:
  Fly    78 KEGNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKL 142

  Fly   154 MMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGES 218
            |.:.|::|.::|||||||||||.:|  .:.||.|||||.:||.||:.|...|.|||:|:|:||||
  Fly   143 MEQEVIVVTLNYRLGALGFLSLPEE--GIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGES 205

  Fly   219 AGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWA---QTPTHINWPYRLAQATG---YTGDANDR 277
            |||:|.|.......||.||||.|:.||:|...|.   :.|....   |||:..|   :.||:...
  Fly   206 AGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTR---RLAELLGGGDFGGDSKAL 267

  Fly   278 DIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMM--RDCWG 340
            ..|...:|...:::|.....:::.:||.:.|. |:|.|.:|...:|...:.:..:|:|  :||.|
  Fly   268 LTFLQSEKATPTAILANTLKVLSPDERRRHLP-FAFKPVVEDSSSPDRFLEQDIMELMHKKDCLG 331

  Fly   341 NSIPMVIGGNSFEGLLMFPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKA--FGKKVRELYFGD 403
             |:|:::|.||.|||.:..:..:  :|.....|...|.|::..:|.|..:|  ....:|..:|..
  Fly   332 -SMPVIMGYNSAEGLAIVVKAKQ--KLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFNG 393

  Fly   404 RTPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVR 468
            :...::.:....||||..:|...:.|.:...|.....:|.:.||.|:.... |:.:.|.....:|
  Fly   394 QALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGR-NLYKKIFQNEDLR 457

  Fly   469 GTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNIPMVCQDEKEQPRGAWLP 533
            |..||||:.||| ..|..:.:....:....:||..|..:||..|.|: |:            |.|
  Fly   458 GVAHADDICYLF-QMAGDETEMNRDDLMVTERLCEMWANFARDGKPS-PI------------WKP 508

  Fly   534 ISK----DDKVFQCLNISHDVHVIDLPEAEKLRLWDCIYDR 570
            :.|    :.....||.|..::.:...|:.|::..|..:|.|
  Fly   509 VKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRR 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	34..564	CDD:395084	179/545 (33%)
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	179/544 (33%)