Protein Alignment alpha-Est8 and nlgn3

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 646
• Identity: 176/646 - (27%)
• Similarity: 269/646 - (41%)
• Gaps: 162/646 - (25%)

  Fly    27 LRSNDKVIADTV---YGKVKGVKW---QSIYG--NNYYSFEGIPFAKPPVGELRFKAPVEPEHWS 83
            |.|:.:|.:.||   |||::|.:.   ..|.|  :.|.   |:|:|.|||||.||..|..|..||
 Frog    27 LSSHAQVYSQTVNTHYGKLRGTRVPLPSEILGPVDQYL---GVPYAAPPVGEKRFLPPEPPPSWS 88

  Fly    84 DVKRCTHVRAKPCQVNIV---------------LKQVQG-----SEDCLYLNVY--TREL----- 121
            .::..||. :..|..||.               |..|.|     ||||||||:|  |.::
 Frog    89 GIRNATHF-SPVCPQNIQNAVPDIMMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVPTEDVKRISK 152

  Fly   122 ----HPHRPL--------------------------------PVLVWIYGGGFQMGEASRDLYSP 150
                .|::.:                                ||:|:|:||.:..|..:
 Frog   153 ECVRKPNKKICRKGGPSAKKQGEELSDNDEDEEGDIRDTGAKPVMVYIHGGSYMEGSGN------ 211

  Fly   151 DYIMME--------HVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGG 207
               |::        :||::.::||:|.|||||..|:.  ..||.||.||:.|||||..|..||||
 Frog   212 ---MIDGSVLASYGNVVVITLNYRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWVSENVAFFGG 271

  Fly   208 DPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTG 272
            ||..|||||...|.:....:.|:..::|||.:.||.|||||:.||.....:.:...||:..|
 Frog   272 DPHRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTRLLAEKVG--- 333

  Fly   273 DANDRDIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRD 337
             .|..|....:...:..|..::.|..|.....|     .:|||.|:     ..|||..|..:|..
 Frog   334 -CNVLDTVDMVDCLRQKSAKELVEQDIQPARYH-----VAFGPVID-----GDVIPDDPEILMEQ 387

  Fly   338 CWGNSIPMVIGGNSFEGLLMFPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFG--------- 393
            ....:..:::|.|..|||       |:.|.:....|..:.:..|..|.......:|
 Frog   388 GEFLNYDIMLGVNQGEGL-------KFVENVVDAEDGVSGSDFDYSVSNFVDNLYGYPEGKDTLR 445

  Fly   394 KKVRELY--FGDR---TPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPL-APTFLYRFDFDS 452
            :.::.:|  :.||   ...|||::.   ||: .:.|  :..::::...||.. :||:.|.|....
 Frog   446 ETIKFMYTDWADRDNPETRRKTLVA---LFT-DHQW--VEPSVVTADLHARYGSPTYFYAFYHHC 504

  Fly   453 KHFNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVV-----HFAISG 512
            :  ::|:....     ...|.|::.|:|..............|.....::|.||     :||.:|
 Frog   505 Q--SLMKPAWA-----DAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTG 562

  Fly   513 DPNIPMVCQDEK---------EQPRGAWLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLW 564
            |||.| |.||.|         |:.  ||...:..|:::  |:|.....|.|...|.|:..|
 Frog   563 DPNKP-VPQDTKFIHTKANRFEEV--AWSKYNPRDQLY--LHIGLKPRVRDHYRATKVAFW 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	174/642 (27%)
		Aes	<116..>221	CDD:223730	45/155 (29%)
nlgn3	XP_012823589.1	COesterase	31..618	CDD:278561	173/640 (27%)
		Aes	<195..>302	CDD:223730	46/117 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910