Protein Alignment alpha-Est8 and nlgn1

DIOPT Version :9

• Sequence 1: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 177/652 - (27%)
• Similarity: 261/652 - (40%)
• Gaps: 163/652 - (25%)

  Fly    25 QRLRSNDKVIADTVYGKVKGVKWQSIYGNN-----YYSFEGIPFAKPPVGELRFKAPVEPEHWSD 84
            |:|...|.|:. |.||||:|.|.:.   ||     ...|.|:|:|.||:||.||:.|..|..|.|
 Frog    46 QKLDDVDPVVL-TTYGKVRGFKKEL---NNEILGPVVQFLGVPYAAPPIGERRFQPPEPPTMWGD 106

  Fly    85 VKRCTHVRAKPCQVNIV---LKQV------------------QGSEDCLYLNVY----------- 117
            :|..|.. |..|..|||   |.:|                  ..||||||||:|
 Frog   107 IKNSTQF-APVCPQNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISK 170

  Fly   118 ---------------------TRELHPHR------------PLPVLVWIYGGGFQMGEASRDLYS 149
                                 |.:|..:.            |.||:|:|:||.:.  |.:.:::.
 Frog   171 ECARKPGKKICRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYM--EGTGNVFD 233

  Fly   150 PDYI-MMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNIT 213
            ...: ...:|:::.::||||.|||||..|:.  ..||.||.|.:.||||...|..||||||..||
 Frog   234 GSVLASYGNVIVITVNYRLGVLGFLSTGDQA--SKGNYGLLDLIQALRWTSENIGFFGGDPLRIT 296

  Fly   214 VFGESAGGASTHYMML---------TDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATG 269
            |||..||.:..:.:.|         ::..||||.:.|..||:||:.||.:.....:...||...|
 Frog   297 VFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVG 361

  Fly   270 YTGDANDRDIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEM 334
                .|..| ...|.:|......:...|......|:.    .:|||.|:     ..|||..|..:
 Frog   362 ----CNMSD-SGELVECLQKKPYRELVDQDIQPVRYH----IAFGPVID-----GDVIPDDPQVL 412

  Fly   335 MRDCWGNSIPMVIGGNSFEGLLMFPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFG------ 393
            |......:..:::|.|..|||       |:.|......|..:.:..|..|.......:|
 Frog   413 MEQGEFLNYDIMLGVNQGEGL-------KFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKD 470

  Fly   394 ---KKVRELY--FGDRT---PGRKTILE-YSDLFSYKYFWHGIHRTLLSRAHHAPL-----APTF 444
               :.::.:|  :.||.   ..|||:|. ::|           |:.:......|.|     :||:
 Frog   471 ILRETIKFMYTDWADRNNPETRRKTLLALFTD-----------HQWVAPAVATADLHSNFGSPTY 524

  Fly   445 LYRFDFDSKHFNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVV--- 506
            .|.|   ..|....::....    ...|.|::.|:|........:.....|.....::|.||
 Frog   525 FYAF---YHHCQTDQVPAWA----DASHGDEIPYVFGIPMIGPTELFPCNFSKNDVMLSAVVMTY 582

  Fly   507 --HFAISGDPNIPMVCQDEK---EQPRG----AWLPISKDDKVFQCLNISHDVHVIDLPEAEKLR 562
              :||.:||||.| |.||.|   .:|..    ||...|:.|:::  |:|.....|.:...|.|:.
 Frog   583 WTNFAKTGDPNQP-VPQDTKFIHTKPNRFEEVAWTRYSQKDQLY--LHIGLKPRVKEHYRATKVN 644

  Fly   563 LW 564
            ||
 Frog   645 LW 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	173/646 (27%)
		Aes	<116..>221	CDD:223730	44/149 (30%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	173/644 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910