Protein Alignment Mics1 and Ghitm

DIOPT Version :9

• Sequence 1: NP_649725.2
• Gene: Mics1 / 40898
• FlyBaseID: FBgn0037506
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_001186051.1
• Gene: Ghitm / 66092
• MGIID: 1913342
• Length: 346
• Species: Mus musculus
• Alignment Length: 320
• Identity: 155/320 - (48%)
• Similarity: 210/320 - (65%)
• Gaps: 7/320 - (2%)

  Fly    48 KSVIPKRNMQELGMRKYSRESRDRDRSQLESRTRGPSLKERMMGPPSENAY---SMGKGAAAGAA 109
            |:.|.|........|:|:.::|.|..   ..:| |..|||..:.|..|..:   .||:...||.|
Mouse    30 KNSITKNQWLVTPSREYATKTRIRTH---RGKT-GQELKEAALEPSMEKIFKIDQMGRWFVAGGA 90

  Fly   110 LMGLVGLCYYGLGLANQPSIYDHSMVWPQYVRDRIHATYAYFGASCGVTAASAVAFFQSDAMMAL 174
            .:||..|||||||::|:....:.:::|||||:||||:||.|...|.|:||.||:|..::.|:|..
Mouse    91 AVGLGALCYYGLGMSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLTALSALAVARTPALMNF 155

  Fly   175 MTRSGWVASLVTLGLVMLSGSIAQGLEYQPGFGAKQLAWLVHCAVLGAVLAPMCLLGGPILTKAL 239
            |....||....|...::.:|.:...:.|:...|.|.|||::|..|:|||:||:.:||||:|.:|.
Mouse   156 MMTGSWVTIGATFAAMIGAGMLVHSISYEQSPGPKHLAWMLHSGVMGAVVAPLTILGGPLLLRAA 220

  Fly   240 LYTSGIVGALSTVAACAPSEKFLHMGGPLAIGLGVVFASSLASMWLPPTTAVGAGLASMSLYGGL 304
            .||:||||.|||||.||||||||:||.||.:|||:||||||.||:||||:..||.|.|:::||||
Mouse   221 WYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFASSLGSMFLPPTSVAGATLYSVAMYGGL 285

  Fly   305 ILFSGFLLYDTQRIVKSAELYPQYSKFPYDPINHALAIYMDALNIFIRIAIILAGDQKRK 364
            :|||.|||||||:::|.||:.|.|....|||||..|.||||.||||:|:|.:||....||
Mouse   286 VLFSMFLLYDTQKVIKRAEITPMYGAQKYDPINSMLTIYMDTLNIFMRVATMLATGSNRK 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mics1	NP_649725.2	GHITM	116..364	CDD:198413	132/247 (53%)
Ghitm	NP_001186051.1	GHITM	82..345	CDD:198413	138/262 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831923
Domainoid	1	1.000	247	1.000	Domainoid score	I2151
eggNOG	1	0.900	-	-		E1_KOG1630
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8667
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2601
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52085
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006240
OrthoInspector	1	1.000	-	-		otm43586
orthoMCL	1	0.900	-	-		OOG6_105770
Panther	1	1.100	-	-	O	PTHR23291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.760