Protein Alignment Mics1 and GHITM

DIOPT Version :9

• Sequence 1: NP_649725.2
• Gene: Mics1 / 40898
• FlyBaseID: FBgn0037506
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_055209.2
• Gene: GHITM / 27069
• HGNCID: 17281
• Length: 345
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 159/336 - (47%)
• Similarity: 213/336 - (63%)
• Gaps: 10/336 - (2%)

  Fly    39 LRT-------PSLAQGKSVIPKRNMQELGMRKYSRESRDRDRSQLESRTRGPSLKERMMGPPSEN 96
            |||       |:..:...|:.....:...:...|||...:.|..:.....|..|||..:.|..|.
Human     9 LRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYATKTRIGIRRGRTGQELKEAALEPSMEK 73

  Fly    97 AY---SMGKGAAAGAALMGLVGLCYYGLGLANQPSIYDHSMVWPQYVRDRIHATYAYFGASCGVT 158
            .:   .||:...||.|.:||..||||||||:|:....:.:::|||||:||||:||.|...|.|:|
Human    74 IFKIDQMGRWFVAGGAAVGLGALCYYGLGLSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLT 138

  Fly   159 AASAVAFFQSDAMMALMTRSGWVASLVTLGLVMLSGSIAQGLEYQPGFGAKQLAWLVHCAVLGAV 223
            |.||:|..::..:|..|.|..||...||...::.:|.:.:.:.|....|.|.||||:|..|:|||
Human   139 ALSAIAISRTPVLMNFMMRGSWVTIGVTFAAMVGAGMLVRSIPYDQSPGPKHLAWLLHSGVMGAV 203

  Fly   224 LAPMCLLGGPILTKALLYTSGIVGALSTVAACAPSEKFLHMGGPLAIGLGVVFASSLASMWLPPT 288
            :||:.:||||:|.:|..||:||||.|||||.||||||||:||.||.:|||:||.|||.||:||||
Human   204 VAPLTILGGPLLIRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSSLGSMFLPPT 268

  Fly   289 TAVGAGLASMSLYGGLILFSGFLLYDTQRIVKSAELYPQYSKFPYDPINHALAIYMDALNIFIRI 353
            |..||.|.|:::||||:|||.|||||||:::|.||:.|.|....|||||..|:||||.||||:|:
Human   269 TVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYMDTLNIFMRV 333

  Fly   354 AIILAGDQKRK 364
            |.:||....||
Human   334 ATMLATGGNRK 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mics1	NP_649725.2	GHITM	116..364	CDD:198413	135/247 (55%)
GHITM	NP_055209.2	GHITM	81..344	CDD:198413	141/262 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141879
Domainoid	1	1.000	249	1.000	Domainoid score	I2132
eggNOG	1	0.900	-	-		E1_KOG1630
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8667
Inparanoid	1	1.050	310	1.000	Inparanoid score	I2605
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52085
OrthoDB	1	1.010	-	-		D1228054at2759
OrthoFinder	1	1.000	-	-		FOG0006240
OrthoInspector	1	1.000	-	-		otm41536
orthoMCL	1	0.900	-	-		OOG6_105770
Panther	1	1.100	-	-	O	PTHR23291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770