DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha-Est9 and tg

DIOPT Version :9

Sequence 1:	NP_731165.2	Gene:	alpha-Est9 / 40897	FlyBaseID:	FBgn0015577	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001316794.1	Gene:	tg / 567631	ZFINID:	ZDB-GENE-030519-1	Length:	2733	Species:	Danio rerio

Alignment Length:	524	Identity:	123/524 - (23%)
Similarity:	213/524 - (40%)	Gaps:	108/524 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEV-------RSCTSQGPKPLQK 97
            ||.|...|.:   :||.  .:|:|:||:|:||:..|||.: ||..       .||...|
Zfish  2182 PITGSDSKRV---TYFL--GVPYARPPIGDLRFSPPQPAD-WTGTWNATFFRSSCLQPG------ 2234

  Fly    98 HFVFEMTD--GSEDCLYLNVYTKNLYPTKPMPVMVWIYGGGFQFGEASRECYSPDYLLR-EDVVV 159
                ::||  .|||||||||:..:.. .|..||:|:.:..|....:.|       ||.. .:::|
Zfish  2235 ----DLTDSSSSEDCLYLNVFVASSV-AKNAPVLVFFHNSGSDLLDGS-------YLAAVGNIIV 2287

  Fly   160 ISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGG 224
            ::.::|:...                  |||......|  |||.||:||..||.||:.|.:.|||
Zfish  2288 VTASFRMAAF------------------GFLSAGSSAL--PGNYGLQDQAAALGWVQKNIALFGG 2332

  Fly   225 DSANITIFGDSAGS--ASVHYMMITEQTHGLFHKAICMSGNTLSPWAVTPQRNWPYRLAVQAGYA 287
            |...:|:..:..|:  ||:|  :.:.....||.:|:.|.|:..||..|.....   ..|..:..|
Zfish  2333 DPTKVTVGAERNGADIASLH--LTSPSASSLFSRALLMGGSVFSPAVVMSSSK---AQAQTSSLA 2392

  Fly   288 GENNTR--DVWEFLK----------NAKGSEIIKANGELCIDEEKKERIGFSFGPVIEPYVTSHC 340
            .|.:.:  |..:.|.          ||..::::..:|.|           .::.||::..
Zfish  2393 RELDCQAADPSQLLDCLRSKPAHSINAAQTKLLAVSGPL-----------QAWSPVVDGN----- 2441

  Fly   341 VVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELDDCR--FVVPI--ELNMDR 401
            ||.:.|...:::...:...:::|....:||:..::...|.:.|....|.:  |...:  .|..|.
Zfish  2442 VVREMPSVALQSGRFHKAEILLGSSFEDGLISRAKNIKNFEQLQGRADSKTAFYAALSNSLGGDD 2506

  Fly   402 ESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFD 466
            .:|..:|.........:.......:.....|:..:.:.  |.|..||.....:|.:..|.:|.:.
Zfish  2507 ANAFVKEAATWFYSLQHSPTPSGYNVFSRALENATRDL--FIICPTVDMAEFWAANTQTGVYMYH 2569

  Fly   467 F-DSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKN--HTREYKCIERLVGLWTHFAAC 528
            . ::..:|.:. ||...         |:.|||...||.:.::  ..:|.....:::....:|...
Zfish  2570 LPENAAYNSVD-LSVPM---------DVQYLFGVPLAAEQRDLFSYKEKTFTLQIMNYMANFIKS 2624

  Fly   529 GNPN 532
            ||||
Zfish  2625 GNPN 2628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	123/524 (23%)
alpha-Est9	NP_731165.2	Aes	<115..>237	CDD:223730	32/122 (26%)
tg	NP_001316794.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930