Protein Alignment alpha-Est9 and nlgn2a

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_009301340.1
• Gene: nlgn2a / 556158
• ZFINID: ZDB-GENE-090918-2
• Length: 828
• Species: Danio rerio
• Alignment Length: 634
• Identity: 160/634 - (25%)
• Similarity: 257/634 - (40%)
• Gaps: 179/634 - (28%)

  Fly    34 VSTTYGPIKGVKRK---SIYG--QSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPK 93
            |:|.||.::|:|::   .|.|  :.|..   :|:|..|:|:.|::.|:.|..|.|||:.|...|.
Zfish    49 VTTNYGKLRGIKKELNNEILGPVEQYLG---VPYATAPIGDRRFQPPEAPGSWQEVRNATQFAPV 110

  Fly    94 -PLQKHFVFE-------MTDG-----------SEDCLYLNVYT---------------------K 118
             |...|.|..       .||.           ||||||||||.                     :
Zfish   111 CPQNVHGVLPEIMLPVWFTDSLDVAATYIQNQSEDCLYLNVYVPTEDGPLTKKHDESTLNRPRDE 175

  Fly   119 NLYPTKPMPVMVWIYGGGFQFGEASRECYSPDYLLR-EDVVVISINYRLGPLGTNDDTWKKKHIF 182
            ::...:..|||::|:||.:.  |.:...:....|.. .:|:|:::|||||.|
Zfish   176 DIRDRRKKPVMLFIHGGSYM--EGTGNMFDASVLAAYGNVIVVTMNYRLGVL------------- 225

  Fly   183 NISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMIT 247
                 |||...|.  ...||.||.||:.||||:..|...||||...|||||..||::.|:.::::
Zfish   226 -----GFLSTGDQ--SAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILS 283

  Fly   248 EQTHGLFHKAICMSGNTLSPWAVTPQRNWPYR----LAVQAGYA-GENNTRDVWEFLKNAKGSEI 307
            ..:.|||.:||..||:.:|.|:::.|   |.:    ||.:.|.. ||  |.|:.:.|:.....|:
Zfish   284 HHSEGLFQRAIAQSGSAISSWSISYQ---PLKYTKILARKVGCTYGE--TADLVDCLRRKNFREL 343

  Fly   308 IKANGELCIDEE-KKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLL 371
                    :|:: :..|...:||||::     ..|||..|..:|:.....|..|:||....|||.
Zfish   344 --------VDQDIQPARYHIAFGPVMD-----GDVVPDDPEILMQQGEFLNYDLLIGVNQGEGLK 395

  Fly   372 LYSETKTNPK----------CLNELDDCRFVVPIELNMDRESA-------LCREYGDQLRQCYYG 419
            ...:..|..:          .::...|..:..|...::.||:.       ..|:.|:..|:...
Zfish   396 FVDDGGTESEEGISAAAFDYTISNFVDNLYGYPKGKDILRETIKFMYTDWADRDNGEMRRKTLL- 459

  Fly   420 DKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKV 484
                :|.|.|:::.         |...|......|  .:|.|.|.|      ::|     |..:.
Zfish   460 ----ALFTDHQWVA---------PAIATAKLHADY--QSPVYFYTF------YHH-----CQTET 498

  Fly   485 R----GTCHGDDLSYLFYNSLARKLKNHTREYKC--------IERLV-GLWTHFAACGNPNFDPE 536
            |    ...|||::.|:|    ...:...|..:.|        :..:| ..||:||..|:||....
Zfish   499 RPEWADAAHGDEIPYVF----GVPMIGATDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNLPVP 559

  Fly   537 QEDLWQPVDPAAVEKHQLKCLNISDELKVIDVPDLKKLMVWESFFRRDE 585
            |:..:....|...|:                       ::|..|..:|:
Zfish   560 QDTKFIHTKPNRFEE-----------------------VIWTKFNSKDK 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	157/602 (26%)
		Aes	<115..>237	CDD:223730	42/143 (29%)
nlgn2a	XP_009301340.1	COesterase	47..608	CDD:306613	160/634 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740