Protein Alignment alpha-Est9 and Ces3a

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_941074.1
• Gene: Ces3a / 382053
• MGIID: 102773
• Length: 571
• Species: Mus musculus
• Alignment Length: 537
• Identity: 146/537 - (27%)
• Similarity: 217/537 - (40%)
• Gaps: 150/537 - (27%)

  Fly    57 FERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPKPLQ--------------KHFVFEMTDGS 107
            |..||||:.|:|.||:.||.||:.|..||..:...|..||              |..:|.:   |
Mouse    63 FLGIPFAQAPLGPLRFSAPLPPQPWEGVRDASINPPMCLQDVERMSNSRFTLNEKMKIFPI---S 124

  Fly   108 EDCLYLNVYTKNLYPTK-----PMPVMVWIYGGGFQFGEASRE------CYSPDYLLREDVVVIS 161
            ||||.||:|:    ||:     ..||||||:||....|.::..      .|.       ||||::
Mouse   125 EDCLTLNIYS----PTEITAGDKRPVMVWIHGGSLLVGSSTSHDGSALAAYG-------DVVVVT 178

  Fly   162 INYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDS 226
            :.||||             ||     |||...|..:  |||.|..|.|.|||||:.|.:.||||.
Mouse   179 VQYRLG-------------IF-----GFLSTGDKHM--PGNRGFLDVVAALRWVQGNIAPFGGDP 223

  Fly   227 ANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSG-------NTLSPWAVTPQRNWPYRLAVQA 284
            ..:||||:|||...|..::::..:.||||:||..||       ..|:.|  :..:|:...:|
Mouse   224 NCVTIFGNSAGGIIVSSLLLSPMSAGLFHRAISQSGVVISKILEDLNAW--SEAQNFANSVA--- 283

  Fly   285 GYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEM 349
              .|..:..::.:.|...:|.::|           .|:.:..|       |..:....|::|.::
Mouse   284 --CGSASPAELVQCLLQKEGKDLI-----------TKKNVNIS-------YTVNDSFFPQRPQKL 328

  Fly   350 MRTAWSNNIPLIIGGVSNE-GLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCR------ 407
            :.......:|.::|..::| |.||.       |..|.||....:...:|..:....|..
Mouse   329 LANKQFPTVPYLLGVTNHEFGWLLL-------KFWNILDKMEHLSQEDLLENSRPLLAHMQLPPE 386

  Fly   408 -------EYGDQ---------LRQCYYGDKTPSLDTL--HEYLQMVSHEYFWFPIYRTVLSRLQY 454
                   ||.|.         ..|...||.|..:.||  .:|||......|.:....|..|   :
Mouse   387 IMPTVIDEYLDNGSDESATRYALQELLGDITLVIPTLIFSKYLQDAGCPVFLYEFQHTPSS---F 448

  Fly   455 ARSAPTYLYRFDFDSKH---FNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTREYKCIE 516
            |:..|.:: :.|..|::   |.            |....|:.|.|.:       ...|.|.|.:.
Mouse   449 AKFKPAWV-KADHSSENAFVFG------------GPFLTDESSLLAF-------PEATEEEKQLS 493

  Fly   517 -RLVGLWTHFAACGNPN 532
             .::..|:.||..||||
Mouse   494 LTMMAQWSQFARTGNPN 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	146/537 (27%)
		Aes	<115..>237	CDD:223730	48/132 (36%)
Ces3a	NP_941074.1	COesterase	36..547	CDD:278561	146/537 (27%)
		Aes	75..>245	CDD:223730	72/203 (35%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832512
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740